Adenomyoma of the Ileum Leading to Intussusception

Abstract

Adenomyoma of the ileum is a rare condition. A 68-year-old Japanese man presented with nausea and distension of the abdomen. Enhanced computed tomography of his abdomen revealed wall thickening in the ileum and dilation of the proximal small intestine. Open laparotomy was performed to find the cause of the patient’s small bowel obstruction, and a tumor was found in the ileum, which had resulted in intussusception. The tumor and 20 cm of the adjacent ileum were resected. The resected specimen displayed a macroscopic appearance suggestive of a submucosal tumor. Histopathological evaluation showed duct cell proliferation and bundles of smooth muscle cells from the mucosa to the serosa, leading to a diagnosis of adenomyoma. Immunohistochemical examination found that cytokeratin 7 and carbohydrate antigen 19-9 were expressed in the duct epithelia. We report a rare case of ileal adenomyoma leading to intussusception in an adult and present the immunohistochemical evaluation of the adenomyoma.

Synchronous adenomyomas of the ileum in an adult‐an exceptional cause of intussusception

“…Clinically, our case presented with intussusceptions caused by adenomyomas of the ileum. To our knowledge, our case is the first report of two synchronous adenomyomas of small intestine, and the third report of adenomyomas causing intestinal intussusceptions in an adult .…”

“…Table 1. Review of the literature: Clinicopathological findings of adenomyoma of the small intestine [6,7].…”

Intussusception Caused by an Adenomyoma of the Ileum: A Case Report.

“…Below, we summarize the characteristics of the 20 previous cases of adenomyoma of the ileum reported in English language literature (table 1) [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30]. Abdominal CT…”

Iron Deficiency Anemia Masking Adenomyoma of the Jejunum

“…5 While the incidence of small intestine adenomyoma is relatively rare, the actual incidence is unclear because very few cases have been reported. Review of the literature reveals 34 reported cases in the small intestine, 3,[5][6][7][8][9][10][11][12][13][15][16][17][18][19][20][21][23][24][25][26][27][28][29][30][31][32][33][34] including the duodenum, ampulla of Vater, and ileum, with 11 well-documented cases reported in the jejunum (Table 1). 3,5,9-10,16-17, 20-21,29,31,34 Of these cases, the patients were between the ages of three to eighty one years old, with six women and five men.…”

“…In the small intestine, intussusception is its most common complication, reported in 19 cases. [1][2][3][6][7][8][11][12][13][15][16][17][18][19][20][24][25]27,[32][33] Anemia has been reported in 11.7% of the cases described (4 cases). A-B, 200x).…”