Adenoma pleomorfo de glándula lagrimal: reporte de un caso pediátrico

Ayala, Paola E.; Dermith, Alejandro M.; Antúnez, Héctor S.; Murillo, Tulio P.

doi:10.1016/j.patol.2018.06.005

Cited by 1 publication

(1 citation statement)

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“…Representan el 5 a 7,5% de todos los tumores intraorbitarios. El tumor epitelial más común de esta glándula es el adenoma pleomórfico, con un porcentaje de 25 al 50% de sus lesiones tumorales 4,5 . El adenoma pleomórfico (ICD-O-Code 8940/0-International Classification of Diseases for Oncology) 6 es un tumor de estructura histológica compleja, con células ductales y mioepiteliocitos organizados en diferentes patrones morfológicos constituyendo conductos, nidos sólidos y láminas que coexisten con áreas estromales hialinizadas, condroides y mixoides.…”

Section: Introductionunclassified

Pleomorphic adenoma of the lacrimal gland: atypical location of a salivary tumor

Rosso¹,

Samar²,

Rodolfo³

et al. 2020

RevFacOdont

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Introduction: In daily ophthalmological practice, lacrimal gland tumors are rare. They represent 5 to 7.5% of all intraorbital tumors. The most common epithelial tumor of this gland is the pleomorphic adenoma, with a percentage of 25 to 50% of its tumor lesions. Objective: In this communication we presented a case of lacrimal gland pleomorphic adenoma and study the expression of Ki67 and the location and expression of MUC-1 and its correlation with tumor prognosis. We also carried out a retrospective descriptive study of the literature on the subject published between 1951 and 2020, using the MEDLINE database. Material and methods: The surgical piece examined, was processed according to the paraffin embedding technique, was performed with a histopathological diagnosis of pleomorphic lacrimal gland adenoma. Histological sections were stained with Hematoxylin / Eosin. Immunostaining with Ki67 and MUC-1 was performed with the DAKO LSAB + kit. Results: The diagnosis of hypercellular pleomorphic adenoma with areas of the remaining lacrimal gland was made. Ki67 labeling was low (≤15%). MUC-1 expression was intense, situated to the apical cell membrane of approximately 10% epitheliocytes from pseudoductal and cystic structures.Conclusions: Through histopathological evaluation, the correlation of Ki67 expression and the location and expression of MUC1, we verified that it is a non-recurrent pleomorphic adenoma without malignant transformation.

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Section: Introductionunclassified