Adenoid Cystic Carcinoma of the Head and Neck

Adenoid cystic carcinoma of the sinonasal tract: outcome of endonasal endoscopic surgery at five-year follow up

“…According to Spiro et al , post-operative radiotherapy probably delays rather than prevents local recurrence 24 . In agreement with previous studies, our findings suggest that a combination of adequate endonasal endoscopic clearance and adjuvant radiotherapy is effective in achieving local control 2 , 4 , 13 , 14 . In the present study, the five-year survival rate was 100 per cent, compared with 50 per cent reported in other studies 13 .…”

“…In the present series, patients presented between the fourth and sixth decades of life, similarly to other studies 11 , 13 , 14 . Earlier series reported that adenoid cystic carcinoma was more common in females, but a recent literature review identified a slight male preponderance 1 , 2 , 13 , 14 . The current series had an equal male:female ratio, perhaps due to the small sample size.…”

Pulmonary Resection for Metastatic Head and Neck Cancer

“…As shown in Figure 2b, our patients with squamous cell carcinoma who had survived more than 2 years also could expect to achieve long-term survival. Adenoid cystic carcinomas are rare tumors, characterized by a slow, protracted course with multiple recurrences [9,14]. As we have shown before, in our study almost all adenoid cystic carcinomas recurred in the lungs.…”

Impact of anatomic site of distant metastasis on survival in salivary gland cancers

“…This caveat is especially of note in the subset of patients with ACC given the prolonged survival seen in a subset of these patients 3,7 . While the median survival of around 30 months in the ACC subgroup of our cohort approximates what has been reported in other series with longer follow‐up, 6,8 the short median follow‐up in our study is certainly of note in this subset given the natural history of metastatic ACC. Additionally, although anatomic site of metastasis was not associated with survival in any of the examined histology subgroups besides ACC, it is important to note that our series may have been underpowered to detect differences in survival within many histologies given small sample sizes in these subgroups.…”