Adenoid Cystic Carcinoma of the Upper Trachea: A Rare Neoplasm

Choudhury, Binoy Kumar; Barman, Geetanjali; Singh, Shobhit; Ahmed, Kuddush

doi:10.4103/2156-7514.119021

Cited by 17 publications

(19 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There are similar cases in the literature of ACC affecting the trachea 13. One report highlights the diagnostic difficulty tracheal ACC presents having been mistaken for asthma for several years before diagnosis and treatment 14…”

Section: Discussionmentioning

confidence: 84%

Airway compromise due to adenoid cystic carcinoma obstructing the distal trachea: a review of current management and clinical trials

Charlton

Pitkin

2015

BMJ Case Reports

View full text Add to dashboard Cite

An 84-year-old man presented with a 2-month history of intermittent stridor and worsening difficulty in breathing. Chest X-ray and flexible nasendoscopy were unremarkable but following further deterioration a CT scan revealed an obstructing lesion in the distal trachea. Bronchoscopy revealed an infiltrative tumour arising 3 cm above the carina causing 90% obstruction. The mass was biopsied and surgically debrided to leave a patent airway. Histological analysis revealed a diagnosis of adenoid cystic carcinoma. Transthoracic surgical resection was unsuccessful and the patient continues to be effectively managed with periodic bronchoscopic debulking and radiotherapy. This case highlights the diagnostic and therapeutic dilemmas posed by distal tracheal lesions and the need for specialist input for effective management.

show abstract

Section: Discussionmentioning

confidence: 84%

Airway compromise due to adenoid cystic carcinoma obstructing the distal trachea: a review of current management and clinical trials

Charlton

Pitkin

2015

BMJ Case Reports

View full text Add to dashboard Cite

show abstract

“…At an advanced stage, infiltration of the trachea wall and adjacent organs frequently occurs, exhibiting a tendency for submucosal dissemination and dissemination along nerves (1,5,6). Long cylindrical structures surrounded by rectangular cells with hyperchromatic nuclei, characteristic of ACC, are visible under a microscope (1).…”

Section: Discussionmentioning

confidence: 99%

Recurrence of adenoid cystic carcinoma of the trachea treated with radical radiotherapy: A case report

2018

View full text Add to dashboard Cite

Abstract. Adenoid cystic carcinoma (ACC) of the trachea is a relatively rare tumor among thoracic diseases. The present study reports the case of a 23-year-old woman with ACC of the trachea who underwent surgical resection of the tumor in The National Institute of Tuberculosis and Lung Diseases (Warsaw, Poland). Histopathological examination revealed that the tumor was not completely resected (R2 resection) and strict observation of the patient was therefore prescribed. After ~9 years of follow-up, clinical and histopathological tumor progression was confirmed and the patient was referred to the Centre of Oncology in Warsaw. The localization and advanced nature of the disease precluded surgical intervention, and radical radiotherapy was therefore performed using intensity-modulated radiation therapy. A total dose of 7,590 Gy, the planning target volume, was administered. A hyperfractionation scheme of radiotherapy was used: 2 fractions of 1.15 Gy daily, with at least a 6 h break in between. Tumor regression was observed following treatment and has been maintained for >3 years, assessed by clinical and computed tomography and positron emission tomography imaging examinations.

show abstract

“…Tracheal malignancies occur in only 0.2 per 100 000 people per year, accounting for under 0.1% of deaths per year . Adenoid cystic carcinoma (ACC) is the second most common malignant tracheal tumor after squamous cell carcinoma . ACC has also been reported to arise in other sites, including breast, lung, lacrimal glands, skin, and uterine cervix …”

Section: Introductionmentioning

confidence: 99%

Fine‐needle aspiration cytology of an adenoid cystic carcinoma of trachea: Common tumor in uncommon location

Kaur

Mitra

Dey

2019

Diagnostic Cytopathology

View full text Add to dashboard Cite

Adenoid cystic carcinoma (ACC) is most often primary in the major and minor salivary glands but can also arise from the submucosal seromucinous glands of the larynx and trachea. We report a case of ACC of the larynx that presented as a recurrent cough for 4 months and vomiting 3 to 4 times within 1 month. Fine-needle aspiration cytology was consistent with an ACC. Subsequent cell block and immunocytochemistry confirmed the diagnosis. This case highlights the need to be aware of unusual lesions that may arise in the region of trachea. K E Y W O R D Sadenoid cystic carcinoma, cytology, fine-needle aspiration, trachea

show abstract

Adenoid Cystic Carcinoma of the Upper Trachea: A Rare Neoplasm

Cited by 17 publications

References 8 publications

Airway compromise due to adenoid cystic carcinoma obstructing the distal trachea: a review of current management and clinical trials

Airway compromise due to adenoid cystic carcinoma obstructing the distal trachea: a review of current management and clinical trials

Recurrence of adenoid cystic carcinoma of the trachea treated with radical radiotherapy: A case report

Fine‐needle aspiration cytology of an adenoid cystic carcinoma of trachea: Common tumor in uncommon location

Contact Info

Product

Resources

About