Adenoid cystic carcinoma of the endometrium

Gernow, Anne; Ahrentsen, O. Dupont

doi:10.1111/j.1365-2559.1989.tb03068.x

Histopathology

1989

DOI: 10.1111/j.1365-2559.1989.tb03068.x

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Adenoid cystic carcinoma of the endometrium

Anne Gernow¹,

O. Dupont Ahrentsen²

Abstract: An adenoid cystic carcinoma of the endometrium co-existing with an endometrioid adenocarcinoma is presented. Immunohistochemical staining for actin and keratin suggests a myoepithelial differentiation of tumour cells in adenoid cystic carcinoma.

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“…The second subtype is characterized by giant cells, and the third subtype is the spindle cell type. Very rare histological patterns of carcinoma, commonly encountered in the uterine cervix, include glassy cell carcinoma ( 2 ) and possibly adenoid cystic carcinoma ( 3 ) .…”

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confidence: 99%

Undifferentiated endometrial carcinoma of the uterus: marked effect of chemotherapy with tetrahydropyranyl-adriamycin, paclitaxel, and carboplatin

Hayashi

Ueda

Takimoto

et al. 2004

Int J Gynecol Cancer

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Undifferentiated endometrial carcinoma of the uterus is rare, and is thought to show a poor prognosis. To date, there is no consensus as to the optimal chemotherapy for this carcinoma. We report a rare case of this carcinoma in a patient who was treated surgically in combination with chemotherapy using a regimen designed by us. This chemotherapy consists of tetrahydropyranyl-adriamycin, paclitaxel, and carboplatin. This regimen is called TTJ [tetrahydropryanyl-adriamycin, taxan (paclitaxel), JM-8 (carboplatin)] chemotherapy and showed a marked effect. The patient was a 52-year-old woman with a giant tumor of the uterus measuring 28 x 18 x 13 cm and weighing 3386 g. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy and omentectomy, but residual carcinoma remained on the surface of the small intestine. Pathologically tumor tissues comprised the whole uterus except for the uterine cervix and there were tumor tissues in the omentum. She was treated with six courses of TTJ chemotherapy without major side-effects. Currently, she remains alive without metastasis 41 months after hysterectomy. This report describes a rare case of undifferentiated endometrial carcinoma of the uterus and introduces TTJ chemotherapy resulting in the remarkable effect on this carcinoma.

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confidence: 99%

Undifferentiated endometrial carcinoma of the uterus: marked effect of chemotherapy with tetrahydropyranyl-adriamycin, paclitaxel, and carboplatin

Hayashi

Ueda

Takimoto

et al. 2004

Int J Gynecol Cancer

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Clear cell metaplasia of the breast

Wells

Viña

1990

Histopathology

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Adenoid cystic carcinoma of the endometrium

Abstract: An adenoid cystic carcinoma of the endometrium co-existing with an endometrioid adenocarcinoma is presented. Immunohistochemical staining for actin and keratin suggests a myoepithelial differentiation of tumour cells in adenoid cystic carcinoma.

Cited by 2 publications

References 5 publications

Undifferentiated endometrial carcinoma of the uterus: marked effect of chemotherapy with tetrahydropyranyl-adriamycin, paclitaxel, and carboplatin

Undifferentiated endometrial carcinoma of the uterus: marked effect of chemotherapy with tetrahydropyranyl-adriamycin, paclitaxel, and carboplatin

Clear cell metaplasia of the breast

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