“…The reported prevalence of intestinal metaplasia in EGMs is less than 20%, 16 and only 4 cases of intestinal metaplasia in an EGM with adenocarcinoma have been reported. 5,17,18 Therefore, the metaplasia-carcinoma sequence is not the major stream of carcinogenesis in adenocarcinoma arising from an EGM of the cervical esophagus. Furthermore, our patient had no gastroesophageal reflux disease endoscopically and symptomatically, and the relation of the carcinogenesis with gastroesophageal reflux disease was not clarified.…”