Adenocarcinoma of the Bladder: Study of 14 Cases and Review of the Literature

Abstract

Fourteen patients with adenocarcinoma of the bladder have been seen over a 14-year period; 6 tumours were of urachal origin and the remaining 8 were primary. All tumours were muscle-infiltrating. The 6 patients with urachal tumours were subjected to surgery; 3 underwent partial cystectomy and 3 radical total cystectomy. All patients who underwent partial cystectomy are alive and free of disease at 60 months, 12 months and 12 months respectively. The other 3 patients who underwent radical cystectomy suffered recurrence and 2 succumbed to their disease within 1 year. All patients with primary adenocarcinoma of the bladder underwent radical cystectomy, 5 of them after planned pre-operative radiotherapy. There were 3 post-operative deaths. One patient died of an unrelated cause 30 months after surgery and 2 died of disseminated disease 8 and 16 months after surgery. One patient developed inguinal lymph node metastases 4 months after surgery and is controlled at 12 months with radiotherapy. Only 1 of the 8 patients with primary adenocarcinoma of the bladder is alive and free of disease at 6 months.

Bladder Tumours in Chinese: A 6 Year Study

“…Histologically, all of the tumours were of an advanced stage and were moderately differentiated. This was similar to those results presented by Kamat et al and Martinez-Pineiro et al 30…”

Primary adenocarcinoma of the urinary bladder:

“…Radical cystectomy with or without adjuvant therapy was used by several authors. The reported 5‐year disease‐free survival was 0–80% [ 2, 24, 26–29, 34–37]. In general, these reports are based on few patients and usually a short follow‐up ( Table 5).…”

Adenocarcinoma vesical primario: nuestra experiencia

“…El adenocarcinoma vesical es un tumor muy infrecuente representando tan sólo entre el 0,5 y el 2% de las neoformaciones vesicales 1,2 . Es más frecuente en varones con una relación de 4,5 a 1, y en la quinta o sexta décadas de la vida 3 , si bien los de origen uracal pueden aparecer en pacientes más jóvenes por su origen en tejidos embriológicos 4 .…”