Adenocarcinoma of Jejunal Duplication Cyst—Case Report and Review of Literature

Abstract

Alimentary tract duplication cyst refers to congenital malformations that involve the mesenteric side of bowel and share a common wall or blood supply with the bowel. Duplication cyst occurs in any segment of the gastrointestinal tract from mouth to anus, but is more commonly seen in the mesentery of the ileo-colic region. Duplication cyst presents more frequently in children with abdominal pain or swelling. In adults, the diagnosis of duplication cyst is incidental and can present with complications like bleed, fistula formation, inflammatory mass, and rarely malignant transformation. English-language literature review has shown only three cases of malignancies reported so far associated with jejunal duplication cyst. A case of incidentally detected metastatic adenocarcinoma in a jejunal duplication cyst is being reported here, along with literature review of malignancies associated with small bowel duplication cyst.

An unusual case of colonic duplication cyst in an adult with dysplasia

“…By definition, they are comprised of a complete duplication of all layers of gastrointestinal tissue, including the mucosa, submucosa and a smooth muscle layer [ 5 , 6 , 8 ]. They often share the smooth muscle layer and the blood supply with the adjacent normal bowel, except for a rare variant of isolated duplication cysts [ 9 , 10 ]. The mucosa may resemble adjacent tissue, or be heterotopic gastric, pancreatic or another type [ 8 , 10 , 11 ].…”

“…They often share the smooth muscle layer and the blood supply with the adjacent normal bowel, except for a rare variant of isolated duplication cysts [ 9 , 10 ]. The mucosa may resemble adjacent tissue, or be heterotopic gastric, pancreatic or another type [ 8 , 10 , 11 ]. In this case, the colonic wall was completely replicated, with additional areas of epithelial ulceration, inflammation and low grade dysplasia.…”