Adenocarcinoma Arising in Gastric Duplication Cyst

Kang, Hyo Jeong; Jang, Se Jin; Park, Young Soo

doi:10.4132/koreanjpathol.2014.48.2.159

Cited by 11 publications

(18 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Adenocarcinoma is currently considered the most common histologic type of malignancy arising in GDC cases; however, neuroendocrine carcinoma and squamous cell carcinoma have also been reported. 7 Table 1 represents an overview of case studies reporting adenocarcinoma arising in GDC. The risk of malignant transformation and associated complications has led to surgical excision being recommended as the standard of care for this condition.…”

Section: Discussionmentioning

confidence: 99%

Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review

Abdulla¹,

Saeed²,

Alshaikh³

et al. 2017

IMCRJ

View full text Add to dashboard Cite

IntroductionAlimentary tract cystic duplication is a rare congenital anomaly predominantly affecting females, and diagnosed mostly in the early years of life.Case reportWe present here a case of a 51-year-old man presenting with a 2-day history of melena. Gastroscopy showed fresh blood, as well as a mass lesion and cavity at the fundus. Biopsies of the mass edge reported the occurrence of moderately differentiated adenocarcinoma and mild chronic gastritis. Computed tomography imaging showed a 5.1×6.5 cm cystic mass in the gastric greater curvature. The patient received six cycles of epirubicin, capecitabine, and oxaliplatin, followed by uncomplicated total gastrectomy.Literature reviewData from all 11 reports of similar cases were reviewed and pooled. The result shows male predominance and variable symptoms, as well as a wide age range (25–76 years) at presentation. The cysts are commonly located along the greater curvature and are unilocular. Surgery was the treatment in most cases.ConclusionAlimentary tract cystic duplication is rare and may predispose to malignancy. Early diagnosis and prompt surgical intervention is important for the best outcome.

show abstract

Section: Discussionmentioning

confidence: 99%

Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review

Abdulla¹,

Saeed²,

Alshaikh³

et al. 2017

IMCRJ

View full text Add to dashboard Cite

show abstract

“…Adenocarcinoma rarely arises from GCP in the unoperated stomach. The difference between adenocarcinoma arising from a GDC and that arising from GCP is the presence of a smooth muscle coat surrounding the lesion in case of the former [ 9 ]. A gastrointestinal stromal tumor (GIST) is also an important differential diagnosis because the stomach is a common location for GISTs.…”

Section: Discussionmentioning

confidence: 99%

“…One-third of GDCs are associated with other developmental anomalies such as GDCs at other locations and duodenal diverticula [1]. Adenocarcinoma rarely arises from a GDC, and only 16 cases of malignancy have been reported to date [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]. An established resection procedure for and the range of this malignancy have not been discovered thus far.…”

Section: Introductionmentioning

confidence: 99%

Adenocarcinoma Arising From a Gastric Duplication Cyst With Lymph Node Metastasis

Kinugasa¹,

Monma²,

Sakamoto

et al. 2020

Cureus

View full text Add to dashboard Cite

Gastric duplication cysts (GDCs) are a relatively rare congenital anomalies and are mostly diagnosed in the early years of life. Herein, we report a very rare surgical case of adenocarcinoma arising from a GDC with lymph node metastasis. A 78-year-old woman was referred to our hospital because of elevated serum levels of cancer antigen (CA) 19-9. Endoscopic ultrasound, contrast fistulography, and computed tomography showed a cystic lesion communicating with the lesser curvature of the stomach. The serum levels of CA 19-9 were high, and fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging demonstrated a slightly enlarged lymph node with high FDG uptake after four months. The size of the cyst was unchanged. It was diagnosed as a GDC. The enlarged lymph node was highly likely to be malignant. Hence, we performed a distal gastrectomy involving the origin of entry and whole body of the GDC with en bloc regional lymphadenectomy. The postoperative pathology was consistent with GDC with moderately differentiated adenocarcinoma and lymph node metastasis. Adjuvant chemotherapy with tegafur-gimeracil-oteracil potassium (S-1) was administered for 12 months. At present, the patient is alive, with no recurrence of the lesion even four years after the operation. GDCs in adults are rare and may predispose to malignancy. Early diagnosis and prompt surgical intervention are important for favorable outcomes.

show abstract

“…Adenocarcinoma arising from GDCs lined by PCCE was not always found in reports, but there are still debates about GDC malignant transformations. [32][33][34][35][36] The author related it to the lasting action of chronic inflammation in duplication cysts. Fuku- moto 33 insists that it is a red alert for those who are identified with GDCs and older than 50, because of continuous exposure to carcinogenic substances.…”

Section: Discussionmentioning

confidence: 99%

Adult Gastric Bronchogenic Cyst With Elevated Tumor Marker in Containing Fluid: A Case Report and Literature Review

Duan

Yan

Zhang

et al. 2019

International Surgery

View full text Add to dashboard Cite

Introduction: Duplication cysts are rare malformations that exist in the alimentary tract, and the mucosa of gastric bronchogenic cyst lined by pseudostratified columnar ciliated epithelium (PCCE) is even more rare. We reviewed related literatures to depict this unique abnormality. Case presentation: Herein we report an abdominal mass that was found incidentally in a 52-year-old female. The biochemical test of contents revealed a high concentration of tumor markers unusually. A laparoscopic surgery was undertaken to remove the lesion. The cyst was found to originate from the stomach but did not show any anatomic communication with the stomach lumen. Pathologic examination confirmed the mucosa was lined by PCCE. Conclusion: The symptoms and radiologic presentations of GDC are nonspecific. It should be distinguished with other abdominal cystic masses. Surgery is advised in respective of malignancy.

show abstract

Adenocarcinoma Arising in Gastric Duplication Cyst

Cited by 11 publications

References 11 publications

Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review

Adenocarcinoma arising from a gastric duplication cyst: a case report and literature review

Adenocarcinoma Arising From a Gastric Duplication Cyst With Lymph Node Metastasis

Adult Gastric Bronchogenic Cyst With Elevated Tumor Marker in Containing Fluid: A Case Report and Literature Review

Contact Info

Product

Resources

About