Adenocarcinoma Arising From a Cervical Esophageal Inlet Patch: The Malignant Potential of a Small Lesion

Abstract

Inlet patches (IP) are heterotopic lesions consisting of gastric mucosa. Commonly located in the cervical esophagus, it is believed that they are remnants of fetal columnar epithelium arising from incomplete replacement during embryogenesis. A rare complication of IP is the development of proximal esophageal adenocarcinoma. We report a case of a 59-year-old male with intractable cough and dysphagia that was found to have a malignant transformation of an IP.

Multidisciplinary treatment of advanced cervical esophageal adenocarcinoma derived from a gastric inlet patch: A case report

“…A gastric inlet patch (GIP) is an ectopic gastric mucosal lesion usually found in the cervical esophagus and is considered an incidental finding, with a reported incidence of ~2.5% ( 3 , 4 ). Given the extreme rarity of GIP-derived EAC, its treatment strategy is notably complex due to its unique location, histology, and limited treatment precedents.…”

Cervical Esophageal Adenocarcinoma Arising From Gastric Inlet Patch: A Benign Lesion With Malignant Potential

“… 1 A gastric inlet patch (GIP) is a lesion of EGM usually found in the cervical esophagus and is considered an incidental finding, with the reported incidence being approximately 2.5%. 1 , 2 The characteristic appearance on endoscopy is a raised lesion, flat plaque, or sessile polyp, which may be solitary or multiple. GIP is typically sharply demarcated and is yellowish brown or deep pink in color but can easily be overlooked on esophagogastroduodenoscopy because of proximity to the esophageal inlet.…”