Adenocarcinoma and (extragonadal) choriocarcinoma of the gallbladder in a young woman

Gallbladder adenocarcinoma with human chorionic gonadotropin: a case report and review of literature

“…Abu-Farsakh and Fraire represented a second case of coexisting adenocarcinoma and choriocarcinoma of the gallbladder [2]. This may be the first case of such tumor documented by positive immunostaining for the βHCG and the increased levels of serum and urinaryβHCG, reported in the English language medical literature.…”

“…One case of adenocarcinoma with choriocarcinomatous element though negative by immunostain [1], two adenocarcinomas with choriocarcinomatous elements [2,3], one adenosquamous cell carcinoma [4], nine undifferentiated carcinomas [5] and another one extrauterine trophoblastic tumor (ETT) [6] have been reported. In other organs, most of the cases with HCG positive, non-gestational tumors have been reported as non-gestational choriocarcincoma in the gastrointestinal tract such as stomach [7-10], esophagus [11], colon [12,13] and jejunum [14].…”

Nongestational choriocarcinoma arising from a primary ovarian tumour

“…Reported sites for nongestational choriocarcinoma include lungs, peritoneum, liver, gall bladder, colon, urinary tract, pineal gland, retroperitoneum, stomach and mediastinum 5–11 …”

Adenocarcinoma of the Gallbladder (Classical Gallbladder Cancer)

“…Mucinous CG with a separate nodule of anaplastic carcinoma was observed (Mizuno et al 1999), and there is a very rare reported case of gallbladder adenocarcinoma associated with a choriocarcinoma, sometimes with immunoreactivity for beta-HCG (Albores-Saavedra et al 1981;Abu-Farsakh and Fraire 1991).…”