Adenocarcinoid Tumors of the Gastrointestinal Tract: Case Report and Review of the Literature

Abstract

Composite adenocarcinoma-carcinoid tumors have been described in the esophagus, stomach, ampulla of Vater and in the colon. These form a distinct pathologic entity in a spectrum of tumors ranging from the pure adenocarcinoma to the pure carcinoid. The biologic behavior, treatment and prognosis of these tumors is determined by the glandular component. We describe two varied clinical presentations in this spectrum, to bring into focus this clinical and pathologic chimera.

Adenocarcinoid tumor of the rectum: a rare finding in a patient with recurrent fistulizing perianal Crohn’s disease

“…Most patients with rectal adenocarcinoid present with rectal bleeding; symptoms of carcinoid syndrome are rare [3]. The management and prognosis of adenocarcinoid tumors are most dependent on the glandular component [3]. Malignancy arising in fistulous tracts in Crohn's disease is rare, with only 61 cases reported from 1950 to 2008 [4].…”

“…Most adenocarcinoid tumors arise in the appendix and only six cases have previously been reported in the rectum, none of which were associated with Crohn's disease [2]. Most patients with rectal adenocarcinoid present with rectal bleeding; symptoms of carcinoid syndrome are rare [3]. The management and prognosis of adenocarcinoid tumors are most dependent on the glandular component [3].…”