Adenine Arabinoside and 5-Mercaptouracil in Herpes Keratitis

Superficial Keratitis

“…Ara-A was originally found to be ineffective in the experimental ocular herpes infection in rabbits, where saturated solution of Ara-A (0.06%) was compared with 0,1 % solution of IDU (Johnson and Jervey, 1964). Later studies showed that due to its low solubility the concentration of Ara-A was too low.…”