Adenine–adenine, adenine–cytosine and cytosine–cytosine intrastrand crosslinks induced by a photoactivatable Pt(<scp>iv</scp>) anticancer prodrug

Lin, Jiafan; Huang, Jingjing; Zhang, Jishuai; Qin, Xinrui; Ma, Ziqi; Wu, Xiaoqin; Wang, Fuyi; Zhao, Yao; Wu, Kui

doi:10.1039/d3dt03351a

Dalton Trans.

2024

DOI: 10.1039/d3dt03351a

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Adenine–adenine, adenine–cytosine and cytosine–cytosine intrastrand crosslinks induced by a photoactivatable Pt(iv) anticancer prodrug

Jiafan Lin,

Jingjing Huang,

Jishuai Zhang

et al.

Abstract: Mass spectrometric analysis revealed the 1,3-ATA/ATC/CTA/CTC crosslinks in trinucleotides by trans-[PtII(py)2]2+ from a photoactivatable diazido Pt(iv) anticancer prodrug upon irradiation.

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Adenine–adenine, adenine–cytosine and cytosine–cytosine intrastrand crosslinks induced by a photoactivatable Pt(iv) anticancer prodrug

Abstract: Mass spectrometric analysis revealed the 1,3-ATA/ATC/CTA/CTC crosslinks in trinucleotides by trans-[PtII(py)2]2+ from a photoactivatable diazido Pt(iv) anticancer prodrug upon irradiation.

Cited by 0 publications

References 31 publications

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