Addressing Prediabetes in Childhood Obesity Treatment Programs: Support from Research and Current Practice

Haemer, Matthew; Grow, H. Mollie; Fernández, Cristina; Lukasiewicz, Gloria; Rhodes, Erinn T.; Shaffer, Laura A.; Sweeney, Brooke; Woolford, Susan J.; Estrada, Elizabeth

doi:10.1089/chi.2013.0158

Cited by 44 publications

(52 citation statements)

References 103 publications

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“…While it is recognized that one of the key goals of pediatric weight management is the prevention of the development of prediabetes and the progression of prediabetes to T2DM, the evidence base to guide care is undeveloped . The Canadian Diabetes Association (CDA) and the ADA recommend screening obese children with 2 risk factors for diabetes every 2 to 3 years .…”

Section: Discussionmentioning

confidence: 99%

The prognosis for glycemic status among children and youth with obesity 2 years after entering a weight management program

et al. 2018

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Section: Discussionmentioning

confidence: 99%

The prognosis for glycemic status among children and youth with obesity 2 years after entering a weight management program

et al. 2018

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“…In observational studies in adults, prediabetes is associated with a higher risk of type 2 diabetes, cardiovascular disease, and cancer . Comparable observations have been reported in children and adolescents with obesity . However, the definition of prediabetes in children is adopted from the adult population, without taking the transient physiological insulin resistance during growth and puberty into consideration …”

Section: Introductionmentioning

confidence: 99%

Impaired fasting glucose and the metabolic profile in Danish children and adolescents with normal weight, overweight, or obesity

et al. 2017

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The prevalence of IFG, when applying the ADA criterion compared with the WHO criterion, was 4 times higher in individuals with overweight and obesity and 14 times higher in individuals with normal weight in this study sample of children and adolescents. IFG was associated with a higher risk of hypertension and dyslipidemia compared with their normoglycemic peers regardless of the definition applied.

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“…Given that up to 50% of newly diagnosed cases of diabetes in the pediatric population are T2D, there is a pressing need to develop and test programs for preventing diabetes in high-risk youth. [54] In particular, these programs must take into account the complex contextual milieu that contributes to disproportionate rates of T2D among youth from minority and low socioeconomic communities. [55] In this report, we have presented the design and methodology for ELSC, a targeted diabetes prevention program for obese Latino youth.…”

Section: Discussionmentioning

confidence: 99%

Culturally-grounded diabetes prevention program for obese Latino youth: Rationale, design, and methods

Williams

Konopken

Keller

et al. 2017

Contemporary Clinical Trials

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Background Type 2 diabetes (T2D) disproportionately impacts Latino youth yet few diabetes prevention programs address this important source of health disparities. Objectives To address this knowledge gap, we describe the rationale, design, and methodology underpinning a culturally-grounded T2D prevention program for obese Latino youth. The study aims to: 1) to test the efficacy of the intervention for reducing T2D risk, 2) explore potential mediators and moderators of changes in health behaviors and health outcomes and, 3) examine the incremental cost-effectiveness for reducing T2D risk. Latino adolescents (N=160, age 14–16) will be randomized to either a 3-month intensive lifestyle intervention or a control condition. The intervention consists of weekly health education delivered by bilingual/bicultural promotores and 3 moderate-to-vigorous physical activity (PA) sessions/week. Control youth receive health information and results from their laboratory testing. Insulin sensitivity, glucose tolerance, and weight-specific quality of life are assessed at baseline, 3-months, 6-months, and 12-months. We will explore whether enhanced self-efficacy and/or social support mediate improvements in nutrition/PA behaviors and T2D outcomes. We will also explore whether effects are moderated by sex and/or acculturation. Cost-effectiveness from the health system perspective will be estimated by the incremental cost-effectiveness ratio using changes in insulin sensitivity at 12-months. Conclusions The results of this study will provide much needed information on how T2D prevention interventions for obese Latino youth are developed, implemented and evaluated. This innovative approach is an essential step in the development of scalable, cost-effective, solution oriented programs to prevent T2D in this and other high-risk populations.

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Addressing Prediabetes in Childhood Obesity Treatment Programs: Support from Research and Current Practice

Cited by 44 publications

References 103 publications

The prognosis for glycemic status among children and youth with obesity 2 years after entering a weight management program

The prognosis for glycemic status among children and youth with obesity 2 years after entering a weight management program

Impaired fasting glucose and the metabolic profile in Danish children and adolescents with normal weight, overweight, or obesity

Culturally-grounded diabetes prevention program for obese Latino youth: Rationale, design, and methods

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