“…Appendix A provides six case studies illustrating the variety of design settings in which methods of the type discussed by Dainoff and colleagues (2020) have been applied to analyze and resolve socio-technical issues in complex system designs as well as the challenges involved in their successful application. Dainoff et al (2020) advocate for the application of a methodological toolset drawn from a set of well-established analytic and design techniques, most of which are drawn from HFE, safety engineering, and systems engineering principles and experience, with much of that experience being from within the nuclear industry itself (e.g., EPRI 2012EPRI , 2015EPRI , 2018Ulrich et al 2012). Additionally, drawing on the systems-based approaches of analysts and investigators, such as Leveson (2011), Hollnagel and Woods (2005), and Rasmussen, Pejtersen and Goodstein (1994), Dainoff and colleagues present their recommendations within the context of a broad, 'work-system' integration approach, focused on achieving the joint optimization of three subsystems:…”