Addressing beta‐lactam allergy: A time for action

Drug hypersensitivity reactions: review of the state of the science for prediction and diagnosis

“…Although DHR has an adverse impact on public health ( MacFadden et al , 2016 ; Phillips et al , 2022 ; Sousa-Pinto et al , 2018a ) and the development of safe new therapeutic products ( Corsini et al , 2018 ; Park et al , 2011 ; Weaver et al , 2020 ), methods and strategies to (1) correctly attribute DHR to a specific mechanism and a specific molecule, and (2) predict the potential for a new chemical entity to cause DHR are not well-established. Thus, there is a major unmet need for new strategies that mitigate the risk of a new chemical to induce allergy.…”