Additive Manufacturing of Bioceramic Scaffolds for Bone Tissue Regeneration with Emphasis on Stereolithographic Processing

Baino, Francesco; Fiume, Elisa; Magnaterra, Giulia; Verné, Enrica

doi:10.1007/978-981-16-4667-6_9

Cited by 2 publications

(1 citation statement)

References 62 publications

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“…Nano-hydroxyapatite scaffolds have also been prepared using other techniques including meltdown, template synthesis, gas foaming and sponge replication 56,58,59 .…”

Section: Other Techniquesmentioning

confidence: 99%

Alveolar Bone Regeneration Via Utilization of Nanohydroxyapatite Scaffolds: A Review

2022

PJMD

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The complete architectural and functional rehabilitation of periodontium owes to the integrity of alveolar bone. The inherent shortcomings of traditional gold standard regenerative procedures like autografting, xenografting, allografting and alloplasting lead to the evolutionary combination of Tissue Engineering/Regenerative Medicine (TE/RM) and nanotechnology for bone repair. Nanotechnology enables the fabrication of either nanoparticles, nanofibers or nanocomposites based on three-dimensional scaffolds. However, it will incorporate vital cells and growth factors in various combinations, to simulate a conducive oral environment of the extracellular matrix (ECM) and empower cells in the bone to regulate in-vivo osteogenesis. The advantageous combination of structural similarity of nanohydroxyapatite (nHA) Scaffolds to the alveolar bone with favorable particle size, response rate, tissue factors and bio factor, makes it attractive for TE/RM. Relevant keywords from 2010-2021 studies were used to retrieve data from "PubMed" and "Google Scholar". This review aims to summarize the cumulative knowledge of commercially available nanohydroxyapatite scaffolds for utilization in alveolar bone augmentation, regeneration of implant osteointegration by their fabrication techniques, advantages, components, types, interaction with various components and particular application of each type for in vivo alveolar bone regeneration. Therefore, nHA scaffolds possess significant osteoconductive and osteoinductive effects on structural similarities to the composition, adhesion and differentiation of bone-forming cells.

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“…Nano-hydroxyapatite scaffolds have also been prepared using other techniques including meltdown, template synthesis, gas foaming and sponge replication 56,58,59 .…”

Section: Other Techniquesmentioning

confidence: 99%

Alveolar Bone Regeneration Via Utilization of Nanohydroxyapatite Scaffolds: A Review

2022

PJMD

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3D-Printed Silk Proteins for Bone Tissue Regeneration and Associated Immunomodulation

Waidi,

Debnath,

Datta

et al. 2024

Biomacromolecules

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Current bone repair methods have limitations, prompting the exploration of innovative approaches. Tissue engineering emerges as a promising solution, leveraging biomaterials to craft scaffolds replicating the natural bone environment, facilitating cell growth and differentiation. Among fabrication techniques, three-dimensional (3D) printing stands out for its ability to tailor intricate scaffolds. Silk proteins (SPs), known for their mechanical strength and biocompatibility, are an excellent choice for engineering 3D-printed bone tissue engineering (BTE) scaffolds. This article comprehensively reviews bone biology, 3D printing, and the unique attributes of SPs, specifically detailing criteria for scaffold fabrication such as composition, structure, mechanics, and cellular responses. It examines the structural, mechanical, and biological attributes of SPs, emphasizing their suitability for BTE. Recent studies on diverse 3D printing approaches using SPs-based for BTE are highlighted, alongside advancements in their 3D and four-dimensional (4D) printing and their role in osteo-immunomodulation. Future directions in the use of SPs for 3D printing in BTE are outlined.

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Additive Manufacturing of Bioceramic Scaffolds for Bone Tissue Regeneration with Emphasis on Stereolithographic Processing

Cited by 2 publications

References 62 publications

Alveolar Bone Regeneration Via Utilization of Nanohydroxyapatite Scaffolds: A Review

Alveolar Bone Regeneration Via Utilization of Nanohydroxyapatite Scaffolds: A Review

3D-Printed Silk Proteins for Bone Tissue Regeneration and Associated Immunomodulation

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