Additive manufacturing in respiratory sciences – Current applications and future prospects

Bock, Simon; Rades, Thomas; Scherließ, Regina

doi:10.1016/j.addr.2022.114341

Cited by 14 publications

(7 citation statements)

References 93 publications

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“…Despite this, researchers and doctors continue to focus on future projections in the health area, with significant advances reported recently in skin modeling using 3D bioprinting methods compatible with human skin [140] . However, bioprinting applications in respiratory sciences have been relatively limited, with only a few studies developing tracheal grafts and lung-on-a-chip models [141] , [142] . Bioprinting has proven incredibly useful in tissue engineering, regenerative medicine, and artificial organ printing.…”

Section: Latest Trends In Am Applied To Medicinementioning

confidence: 99%

Future trends of additive manufacturing in medical applications: An overview

Amaya-Rivas,

Perero,

Helguero

et al. 2024

Heliyon

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Section: Latest Trends In Am Applied To Medicinementioning

confidence: 99%

Future trends of additive manufacturing in medical applications: An overview

Amaya-Rivas,

Perero,

Helguero

et al. 2024

Heliyon

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“…Frequently, comprehensive knowledge of the underlying medical condition is necessary for the most successful treatment approach. Similarly, the utilization of synthetic 3D lung tissues using graphene-aerogel would allow a fundamental investigation for a realistic simulation of the necessary systems [ 201 ]. To solve a few of the constraints of the 3D printing technology, the optimization of cell-construct functional responses and the complex dynamics of natural tissue products should be investigated.…”

Section: Coronavirus Disease (Covid-19)mentioning

confidence: 99%

Emerging Trends in Nanotechnology: Aerogel-Based Materials for Biomedical Applications

et al. 2023

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At present, aerogel is one of the most interesting materials globally. The network of aerogel consists of pores with nanometer widths, which leads to a variety of functional properties and broad applications. Aerogel is categorized as inorganic, organic, carbon, and biopolymers, and can be modified by the addition of advanced materials and nanofillers. Herein, this review critically discusses the basic preparation of aerogel from the sol–gel reaction with derivation and modification of a standard method to produce various aerogels for diverse functionalities. In addition, the biocompatibility of various types of aerogels were elaborated. Then, biomedical applications of aerogel were focused on this review as a drug delivery carrier, wound healing agent, antioxidant, anti-toxicity, bone regenerative, cartilage tissue activities and in dental fields. The clinical status of aerogel in the biomedical sector is shown to be similarly far from adequate. Moreover, due to their remarkable properties, aerogels are found to be preferably used as tissue scaffolds and drug delivery systems. The advanced studies in areas including self-healing, additive manufacturing (AM) technology, toxicity, and fluorescent-based aerogel are crucially important and are further addressed.

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“…98,99 Under the hypoxic condition, the tissue undergoes immense stress due to nutritional deprivation and the accumulation of reactive oxygen species (ROS); it fails to maintain cellular activity and undergoes necrosis. 100,101 In tissue engineering, various solid and liquid peroxides, fluorides, and percarbonates have been used as popular bioink additives to initiate cellular gaseous exchange through bioscaffold layers. 98,99,102 These oxygen-generating substances (OGSs) produce hydrogen peroxide (H 2 O 2 ) when exposed to water; subsequently, the H 2 O 2 dissociates into water and oxygen.…”

Section: Intravital 3d Bioprinting (I3d)mentioning

confidence: 99%

“…Additionally, the biofabrication of large constructs requires efficient oxygen transfer through tissue layers to maintain various metabolic processes and signaling cascades. Oxygen plays a vital role in maintaining physiological function and an adequately oxidizing environment. , Under the hypoxic condition, the tissue undergoes immense stress due to nutritional deprivation and the accumulation of reactive oxygen species (ROS); it fails to maintain cellular activity and undergoes necrosis. , …”

Section: Promising Strategies For 3d Biofabricationmentioning

confidence: 99%

The Art of Building Living Tissues: Exploring the Frontiers of Biofabrication with 3D Bioprinting

Verma,

Khanna,

Kumar

et al. 2023

ACS Omega

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The scope of three-dimensional printing is expanding rapidly, with innovative approaches resulting in the evolution of state-of-the-art 3D bioprinting (3DbioP) techniques for solving issues in bioengineering and biopharmaceutical research. The methods and tools in 3DbioP emphasize the extrusion process, bioink formulation, and stability of the bioprinted scaffold. Thus, 3DbioP technology augments 3DP in the biological world by providing technical support to regenerative therapy, drug delivery, bioengineering of prosthetics, and drug kinetics research. Besides the above, drug delivery and dosage control have been achieved using 3D bioprinted microcarriers and capsules. Developing a stable, biocompatible, and versatile bioink is a primary requisite in biofabrication. The 3DbioP research is breaking the technical barriers at a breakneck speed. Numerous techniques and biomaterial advancements have helped to overcome current 3DbioP issues related to printability, stability, and bioink formulation. Therefore, this Review aims to provide an insight into the technical challenges of bioprinting, novel biomaterials for bioink formulation, and recently developed 3D bioprinting methods driving future applications in biofabrication research.

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Additive manufacturing in respiratory sciences – Current applications and future prospects

Cited by 14 publications

References 93 publications

Future trends of additive manufacturing in medical applications: An overview

Future trends of additive manufacturing in medical applications: An overview

Emerging Trends in Nanotechnology: Aerogel-Based Materials for Biomedical Applications

The Art of Building Living Tissues: Exploring the Frontiers of Biofabrication with 3D Bioprinting

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