Additive effect of propofol for attenuation of hypertension in a patient with undiagnosed phaeochromocytoma

Işik, A.Geylan; Taydas, Eren; Ulukaya, Sezgin; Balcioglu, Taner; Ünal, Aydın; Kilic, Murat

doi:10.1017/s0265021507000099

Cited by 6 publications

(6 citation statements)

References 2 publications

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“…Hypotension is a common side effect associated with propofol use due to vasodilation and negative inotropic effect (28,29). The present study demonstrated that, compared with propofol, sevoflurane kept hemodynamics stable.…”

Section: Discussionsupporting

confidence: 55%

Sevoflurane may be more beneficial than propofol in patients receiving endoscopic variceal ligation and endoscopic variceal sclerotherapy: A randomized, double-blind study

Tang

Liu

et al. 2017

Experimental and Therapeutic Medicine

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Abstract. The aim of the present study was to evaluate the safety and efficacy of various general anesthesia regimens during endoscopic variceal ligation (EVL) and endoscopic variceal sclerotherapy (EVS). A total of 123 patients with American Society of Anesthesiologists physical status III and IV, aged 40-70 years, undergoing general anesthesia for EVL and EVS were randomly divided into two groups: Sevoflurane anesthesia (group S; n=60) and propofol anesthesia (group P; n=60). Vital signs, particularly heart rate (HR) and mean arterial pressure (MAP), were monitored. The designated time points were as follows: 5 min before induction (T0), and 1, 5, 10, 15, 20, 25 and 30 min after intubation (T1, T2, T3, T4, T5, T6 and T7, respectively). Time intervals were recorded, including recovery time and extubation time. Following surgery, the observer recorded the Ramsay sedation scale (RSS) score and the visual analogue scale (VAS) score. Adverse reactions were noted. Results demonstrated that there were significant differences in MAP between the two groups at T2, T3, T5, T6 and T7 (P<0.05). There was a significant difference in HR between the two groups at T2, T3 and T4 (P<0.05). Recovery time and extubation time in group P were significantly longer than those in group S (P<0.05; 18.38±2.25 min vs. 14.57±1.04 min and 21.70±2.70 min vs. 15.83±0.88 min, respectively). The rate of ephedrine injected was 58.3% (35/60 patients) in group P vs. 28.3% (17/60 patients) in group S (P<0.05). There was a significant difference in the RSS score between the two groups 5 min after extubation (P<0.05). VRS scores demonstrated that anesthetists and patients were significantly more satisfied with the procedure in group S than in group P (P<0.01). In conclusion, the superiority and special clinical value of inhalational anesthesia has been demonstrated during EVL and EVS attributed to stable hemodynamics and high quality of anesthesia recovery in the present study.

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Section: Discussionsupporting

confidence: 55%

Sevoflurane may be more beneficial than propofol in patients receiving endoscopic variceal ligation and endoscopic variceal sclerotherapy: A randomized, double-blind study

Tang

Liu

et al. 2017

Experimental and Therapeutic Medicine

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“…Further research into propofol effects and phaeochromocytoma may be needed. We thank Dr Fassam for his interest in our study and his comments [1]. We agree with him that the use of beta blockers is not a favourable option and has limited indications during arrhythmias in case of phaeochromocytoma.…”

mentioning

confidence: 52%

“…I read with interest the letter by Isik and colleagues [1] describing the attenuation effects of propofol in a case with undiagnosed phaeochromocytoma. Management of patients with pheochromocytoma is very challenging, especially if undiagnosed and unprepared.…”

mentioning

confidence: 99%

Additive effect of propofol for attenuation of hypertension in a patient with undiagnosed phaeochromocytoma

Rassam

2008

European Journal of Anaesthesiology

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“…'s study. [ 11 ] However, it caused short-time reductions in BP. Beta-blockers are among preferred agents in patients with intraoperative tachycardia and hypertension or in patients with treated pheochromocytoma that developed intraoperative tachycardia and hypertension.…”

Section: Discussionmentioning

confidence: 99%

Management of anesthesia in unspecified extra-adrenal pheochromocytoma patient who used beta-blocker

et al. 2014

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An operation was planned for a female patient aged 59 for intra-abdominal mass. The patient was using nebivolol for hypertension. Blood pressure (BP) of the patient was raised to 200/130 mmHg during anesthesia induction. BP was gradually reduced by remifentanil infusion. Following the manipulation of the mass, BP began to increase (225/160 mmHg), thus nitroglycerin and followed nitroprusside infusion was started. Propofol (200 + 200 mg) and furosemide (20 mg) were administered intravenously. BP suddenly dropped (90/60 mmHg) following the removal of the mass, nitroglycerine, and nitroprusside infusions were stopped; remifentanil dose was decreased and fluid was quickly infused. The patient was uneventually recovered. Vanilmandelic acid level was higher in the patient and pheochromocytoma was considered.

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Additive effect of propofol for attenuation of hypertension in a patient with undiagnosed phaeochromocytoma

Cited by 6 publications

References 2 publications

Sevoflurane may be more beneficial than propofol in patients receiving endoscopic variceal ligation and endoscopic variceal sclerotherapy: A randomized, double-blind study

Sevoflurane may be more beneficial than propofol in patients receiving endoscopic variceal ligation and endoscopic variceal sclerotherapy: A randomized, double-blind study

Additive effect of propofol for attenuation of hypertension in a patient with undiagnosed phaeochromocytoma

Management of anesthesia in unspecified extra-adrenal pheochromocytoma patient who used beta-blocker

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