Additive effect of dorzolamide hydrochloride to patients taking travoprost: A retrospective study

Boyer, Stephen

doi:10.1016/j.optm.2008.01.019

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Cited by 3 publications

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“…Miosis can be a serious side effect in older people especially at night and, in part, caused the decline in popularity of the clinical use of the cholinergic agents 20 . Day‐time miosis is generally avoided in people by the evening instillations of prostaglandins.…”

Section: Discussionmentioning

confidence: 99%

Dose response for travoprost^®in the glaucomatous beagle

MacKay

McLaughlin

Plummer

et al. 2011

Veterinary Ophthalmology

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Section: Discussionmentioning

confidence: 99%

Dose response for travoprost^®in the glaucomatous beagle

MacKay

McLaughlin

Plummer

et al. 2011

Veterinary Ophthalmology

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Influence of various concentrations of terpene-4-ol enhancer and carbopol-934 mucoadhesive upon the in vitro ocular transport and the in vivo intraocular pressure lowering effects of dorzolamide ophthalmic formulations using albino rabbits

Afouna

Khedr

Abdel-Naim

et al. 2010

Journal of Pharmaceutical Sciences

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Ocular hypotensive effect, preservation of visual fields, and safety of adding dorzolamide to prostaglandin therapy for twelve months

Inoue

Masumoto²,

Wakakura³

et al. 2011

OPTH

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Purpose:To prospectively evaluate the safety, hypotensive effect, and preservation of visual fields of dorzolamide when added to latanoprost.Subjects and methods:This study included 46 patients (46 eyes) with primary open-angle glaucoma who had been treated with latanoprost. Dorzolamide (1%) was added to latanoprost, and the intraocular pressure (IOP) was monitored before and after 3, 6, and 12 months. The mean deviation shown by Humphrey perimetry was compared before and after twelve months of treatment. Adverse reactions were monitored over the 12-month study period.Results:The mean baseline IOP was 17.2 ± 3.0 mmHg while those after 3, 6 and 12 months of treatment were 14.9 ± 3.0 mmHg, 14.5 ± 3.2 mmHg, and 14.6 ± 2.6 mmHg respectively (P < 0.0001, 1-β(power) = 0.9999571). The absolute reduction of IOP and the percent reduction were similar after 3, 6, and 12 months of treatment. The mean deviation on Humphrey perimetry was similar before and after twelve months of treatment. Three patients discontinued dorzolamide therapy due to elevation of IOP and one patient discontinued it because of adverse reactions.Conclusion:Dorzolamide is safe and effective when used for twelve months as add-on therapy to latanoprost for open-angle glaucoma.

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Additive effect of dorzolamide hydrochloride to patients taking travoprost: A retrospective study

Cited by 3 publications

References 18 publications

Dose response for travoprost^®in the glaucomatous beagle

Dose response for travoprost^®in the glaucomatous beagle

Influence of various concentrations of terpene-4-ol enhancer and carbopol-934 mucoadhesive upon the in vitro ocular transport and the in vivo intraocular pressure lowering effects of dorzolamide ophthalmic formulations using albino rabbits

Ocular hypotensive effect, preservation of visual fields, and safety of adding dorzolamide to prostaglandin therapy for twelve months

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Additive effect of dorzolamide hydrochloride to patients taking travoprost: A retrospective study

Cited by 3 publications

References 18 publications

Dose response for travoprost®in the glaucomatous beagle

Dose response for travoprost®in the glaucomatous beagle

Influence of various concentrations of terpene-4-ol enhancer and carbopol-934 mucoadhesive upon the in vitro ocular transport and the in vivo intraocular pressure lowering effects of dorzolamide ophthalmic formulations using albino rabbits

Ocular hypotensive effect, preservation of visual fields, and safety of adding dorzolamide to prostaglandin therapy for twelve months

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Product

Resources

About

Dose response for travoprost^®in the glaucomatous beagle

Dose response for travoprost^®in the glaucomatous beagle