Addition of local antiseptic spray to parenteral antibiotic regimen reduces the incidence of stomal infection following percutaneous endoscopic gastrostomy: a randomized controlled trial

Abstract

A combination of cefuroxime and Betadine spray significantly reduces stomal infection following percutaneous endoscopic gastrostomy at the end of week 1. Both the antibiotic group (A) and the combined group (C) did well compared with the Betadine only group (B) at midweek.

Antibacterial gauzes are effective in preventing infections after percutaneous endoscopic gastrostomy placement

“…However, glycerin-containing gauzes are bacteriostatic (glycerin concentration of 65%), whereas the PHMB gauzes that we used are bactericidal. The addition of betadine to antibiotic prophylaxis reduced the number of infections (9%) in a small trial, but the use of betadine spray alone led to high infection rates (43%) [27].…”

Clinical practice guidelines for antimicrobial prophylaxis in surgery

“…292 Choice of agent. The most frequently used agents for gastroduodenal procedures were firstgeneration 271,273,277,278,284,[293][294][295][296][297] and second-generation 269,270,274,275,280,293,294,298 cephalosporins. No differences in efficacy between first-and secondgeneration cephalosporins were found.…”

Airway Infection Predisposes to Peristomal Infection after Percutaneous Endoscopic Gastrostomy with High Concordance Between Sputum and Wound Isolates

“…[1][2][3][4][5] Even though covering pull-type PEG tube or push-type method may prevent infection, the standard "pull method" is still the most widely used technique because it is well established. [5][6][7][8] In the procedure, the gastrostomy catheter will be passed through the mouth and oropharynx until reaching the abdominal wall. Thus, oropharyngeal microorganisms may be transported to cause peristomal infection.…”