“…Fluoride released from restorations is a clinically available and safe method because fluoride increases the acid resistance of the adjacent tooth and exerts a cariostatic effect [Skartveit et al, 1990;Forss and Seppä, 1990;Griffin et al, 1992;Mukai et al, 1993;ten Cate and Van Duinen, 1995]. As a result the addition of fluoride to a number of filling materials has been investigated [Bitner and Wei, 1973; Forsten, 1976;Swartz et al, 1976]. Recently, resin composites have been selected as restorative materials and the release of fluoride from these materials evaluated [Dijkman and Arends, 1992;Dijkman et al, 1993;Donly and Gomez, 1994;Kawai et al, 1997].…”