Iron (Fe)-salts are widely used as the inorganic chemical coagulants for water and wastewater treatment processes. In retrospect, Fe-salts application in different domains of the urban wastewater system (UWWS) (e.g. sewers, bioreactor, digester) has been in isolation. The choice and application of Fe-salts are at present primarily driven by considerations merely at the subsystem level, with their I acknowledge that the copyright of all material contained in my thesis resides with the copyright holder(s) of that material. Where appropriate I have obtained copyright permission from the copyright holder to reproduce material in this thesis and have sought permission from co-authors for any jointly authored works included in the thesis. vi Publications during candidature Peer-reviewed scientific journal articles • Sohan Shrestha, Keshab Sharma, Zhongwei Chen, Zhiguo Yuan (2019). Unravelling the influences of sewer-dosed iron salts on activated sludge properties with implications on settleability, dewaterability and sludge rheology.