Addenbrooke's Cognitive Examination III: un test neuropsicológico útil para el cribado y la obtención de perfiles cognitivos

Matías‐Guiu, Jorge; Fernández-Bobadilla, Ramón; Cortés‐Martínez, Ana

doi:10.1016/j.nrl.2016.06.014

Cited by 9 publications

(12 citation statements)

References 9 publications

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“…These other tasks grouped in 5 domains may be useful to establish a cognitive profile, as we have previously demonstrated in a prior investigation [33]. Thus, the ACE-III may probably be regarded as a relatively brief cognitive instrument with a major role in screening (i.e., detection, optimally with the Mini-ACE) as well as in establishing a cognitive profile (i.e., helping in the differential diagnosis) [34]. …”

Section: Discussionmentioning

confidence: 99%

“…The usefulness of memory scores of each test might suggest a potential application in earlier stages of AD. For instance, the memory score of the ACE-III yielded a high correlation with the Free and Cued Selective Reminding Test and demonstrated a high diagnostic accuracy for amnestic mild cognitive impairment [34]. In addition, comparison of the different memory scores may suggest that those tasks that are more ecological and related to everyday functioning (e.g., remembering the shopping list in the RUDAS or a name and an address in the ACE-III) provide a better discrimination than memory tasks using a list of words.…”

Section: Discussionmentioning

confidence: 99%

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Comparative Diagnostic Accuracy of the ACE-III, MIS, MMSE, MoCA, and RUDAS for Screening of Alzheimer Disease

Matías‐Guiu

Valles‐Salgado²,

Rognoni³

et al. 2017

Dement Geriatr Cogn Disord

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Background: Our aim was to evaluate and compare the diagnostic properties of 5 screening tests for the diagnosis of mild Alzheimer disease (AD). Methods: We conducted a prospective and cross-sectional study of 92 patients with mild AD and of 68 healthy controls from our Department of Neurology. The diagnostic properties of the following tests were compared: Mini-Mental State Examination (MMSE), Addenbrooke's Cognitive Examination III (ACE-III), Memory Impairment Screen (MIS), Montreal Cognitive Assessment (MoCA), and Rowland Universal Dementia Assessment Scale (RUDAS). Results: All tests yielded high diagnostic accuracy, with the ACE-III achieving the best diagnostic properties. The area under the curve was 0.897 for the ACE-III, 0.889 for the RUDAS, 0.874 for the MMSE, 0.866 for the MIS, and 0.856 for the MoCA. The Mini-ACE score from the ACE-III showed the highest diagnostic capacity (area under the curve 0.939). Memory scores of the ACE-III and of the RUDAS showed a better diagnostic accuracy than those of the MMSE and of the MoCA. All tests, especially the ACE-III, conveyed a higher diagnostic accuracy in patients with full primary education than in the less educated group. Implementing normative data improved the diagnostic accuracy of the ACE-III but not that of the other tests. Conclusions: The ACE-III achieved the highest diagnostic accuracy. This better discrimination was more evident in the more educated group.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Comparative Diagnostic Accuracy of the ACE-III, MIS, MMSE, MoCA, and RUDAS for Screening of Alzheimer Disease

Matías‐Guiu

Valles‐Salgado²,

Rognoni³

et al. 2017

Dement Geriatr Cogn Disord

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“…In the present study, the cognition levels did not differ significantly between the two groups but indicated important deficits in many cognitive domains before rehabilitation treatment in both these groups. ACE III was used as a well-tolerated screening score which permits differentiation of patients with cognitive impairment, including those with BTs [22,23,42]. This questionnaire is a more sensitive cognition tool than the mini-mental state examination (MMSE) in BT patients.…”

Section: Discussionmentioning

confidence: 99%

“…Cognitive function was evaluated using the Addenbrooke's Cognitive Examination III (ACE III). The ACE III is a screening questionnaire that is capable of differentiating patients with and without cognitive impairment [22]. The ACE III consists of 21 questions, with a total score of 100.…”

Section: Cognitive Function Assessmentmentioning

confidence: 99%

“…The results of each task are scored to give a total amount of 100 points (18 points for attention, 26 for memory, 14 for fluency, 26 for language, and 16 for visuospatial processing). The score needs to be interpreted in the context of a patient's overall history and clinical examination [22,23]. The ACE III includes different scores for each function, in addition to the general score, to observe the progression of cognitive deficits over time [24].…”

Section: Cognitive Function Assessmentmentioning

confidence: 99%

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Can Multidisciplinary Inpatient and Outpatient Rehabilitation Provide Sufficient Prevention of Disability in Patients with a Brain Tumor?—A Case-Series Report of Two Programs and A Prospective, Observational Clinical Trial

Hojan

Gerreth

2020

IJERPH

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Brain tumor (BT) patients have a high incidence of disability due to the effects of the tumor itself or oncological treatment. Despite the incidence of neurological and functional deficits caused by BT, rehabilitation of those patients is not as properly established as in patients with other neurological conditions. The aim of the research was to evaluate the effectiveness of a multidisciplinary rehabilitation, carried out as an out- or in-patient program, as prevention of disability in BT patients. This was developed as a case-series report of two programs and a prospective, observational clinical study in BT patients who were allocated to inpatient (n = 28) or outpatient (n = 26) rehabilitation programs. The patients were assessed using the Barthel Index, Berg Balance Scale, Functional Independence Measure (FIM), Functional Assessment of Cancer Therapy—Brain and Cognitive Function, and Addenbrooke’s Cognitive Examination III (ACE III) upon admission and after 12 weeks of rehabilitation. Analysis of the results showed that patients in both programs significantly improved their physical functioning scores in daily activities (p < 0.0001). We also observed significant reductions in most post-intervention cognitive complaints (p < 0.05), except for the FIM social functioning and ACE III language functioning in the outpatient group (p > 0.05) in contrast to inpatients (p < 0.001). This is evidence that early multidisciplinary rehabilitation is an effective therapeutic strategy to reduce BT symptoms and disability in this group of patients.

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