Added value of Mindfulness-Based Cognitive Therapy for Depression: A Tree-based Qualitative Interaction Analysis

Avest, Marleen J. ter; Dusseldorp, Elise; Huijbers, Marloes J.; Aalderen, Joël R. van; Cladder‐Micus, Mira B.; Spinhoven, Philip; Greven, Corina U.; Speckens, Anne E. M.

doi:10.1016/j.brat.2019.103467

Cited by 8 publications

(4 citation statements)

References 52 publications

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“…In clinical settings, our IPD meta-analysis of mindfulness-based cognitive therapy (MBCT) to prevent recurrent depression relapse has found that those with worse baseline mental health would benefit more 34 . Another analysis combining three clinical trials has found a similar interaction effect 35 . However, some studies have found no evidence of such an interaction 36 .…”

Section: Individual-level Factorsmentioning

confidence: 81%

Systematic review and individual participant data meta-analysis of randomized controlled trials assessing mindfulness-based programs for mental health promotion

Galante

Friedrich

Aeamla-Or³

et al. 2023

Nat. Mental Health

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Mindfulness-based programs (MBPs) are widely used to prevent mental ill health. Evidence suggests beneficial average effects but wide variability. We aimed to confirm the effect of MBPs and to understand whether and how baseline distress, gender, age, education, and dispositional mindfulness modify the effect of MBPs on distress among adults in non-clinical settings. We conducted a systematic review and individual participant data (IPD) meta-analysis (PROSPERO CRD42020200117). Databases were searched in December 2020 for randomized controlled trials satisfying a quality threshold and comparing in-person, expert-defined MBPs with passive-control groups. Two researchers independently selected, extracted and appraised trials using the revised Cochrane Risk-of-Bias tool. IPD of eligible trials were sought from authors. The primary outcome was psychological distress (unpleasant mental or emotional experiences including anxiety and depression) at 1 to 6 months after program completion. Data were checked and imputed if missing. Pairwise, random-effects, two-stage IPD meta-analyses were conducted. Effect modification analyses followed a within-studies approach. Stakeholders were involved throughout this study. Fifteen trials were eligible; 13 trialists shared IPD (2,371 participants representing 8 countries. In comparison with passive-control groups, MBPs reduced average distress between 1 and 6 months post-intervention with a small to moderate effect size (standardized mean difference, −0.32; 95% confidence interval, −0.41 to −0.24; P < 0.001; no heterogeneity). Results were robust to sensitivity analyses and similar for the other timepoint ranges. Confidence in the primary outcome result is high. We found no clear indication that this effect is modified by the pre-specified candidates. Group-based teacher-led MBPs generally reduce psychological distress among volunteering community adults. More research is needed to identify sources of variability in outcomes at an individual level.

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Section: Individual-level Factorsmentioning

confidence: 81%

Systematic review and individual participant data meta-analysis of randomized controlled trials assessing mindfulness-based programs for mental health promotion

Galante

Friedrich

Aeamla-Or³

et al. 2023

Nat. Mental Health

Self Cite

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“…Emerging evidence suggests that individuals who are more at risk benefit more from emotion regulation interventions [ 89 ]. Furthermore, a recent study found that a mindfulness intervention was more effective for those patients with an earlier onset of depression, higher levels of rumination and a lower quality of life [ 90 ]. Similar results were obtained for healthy participants with higher levels of neuroticism [ 24 , 25 ] or stress [ 91 ].…”

Section: Discussionmentioning

confidence: 99%

Who Benefits Most? Interactions between Personality Traits and Outcomes of Four Incremental Meditation and Yoga Treatments

Matko

Berghöfer

Jeitler

et al. 2022

JCM

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Mind–Body Medicine (MBM) includes a broad range of interventions with proven preventive and clinical value, such as yoga and meditation. However, people differ in their preferences and response to different MBM treatments and it remains unclear who benefits most from what type of practice. Thus, finding moderators of treatment outcome seems to be a promising approach. This was the aim of the present study. We conducted a single-case multiple-baseline study investigating the outcomes and moderators of four different MBM treatments. Fifty-seven healthy participants with no prior experience were randomly assigned to three baselines (7, 14, and 21 days) and four eight-week treatments: mantra meditation alone, meditation plus physical yoga, meditation plus ethical education and meditation plus yoga and ethical education. We analysed the data using effect size estimation, multiple regression and cluster analyses. High anxiety, high absorption, low spirituality, low openness and younger age were associated with a range of positive outcomes, such as increased wellbeing or decentering and decreased mind wandering. Receiving ethical education consistently improved wellbeing, while engaging in physical yoga reduced mind wandering. In the cluster analysis, we found that participants with a more maladaptive personality structure enhanced their emotion regulation skills more. Consequently, people do differ in their response to MBM interventions and more vulnerable people, or those high in absorption, seem to benefit more. These findings could support the development of custom-tailored MBM interventions and help clinicians to make scientifically sound recommendations for their patients.

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“…The result of an analysis with QUINT is a binary tree from which treatment assignment criteria can be derived. Study results suggested that MBCT might be more beneficial for patients with earlier onset of depression, higher levels of rumination and a lower quality of life (Ter Avest et al, 2019).…”

mentioning

confidence: 94%

Cognitive-behavioural therapy and personalized treatment: An introduction to the special issue

Spinhoven

Cuijpers

Hollon

2020

Behaviour Research and Therapy

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Added value of Mindfulness-Based Cognitive Therapy for Depression: A Tree-based Qualitative Interaction Analysis

Cited by 8 publications

References 52 publications

Systematic review and individual participant data meta-analysis of randomized controlled trials assessing mindfulness-based programs for mental health promotion

Systematic review and individual participant data meta-analysis of randomized controlled trials assessing mindfulness-based programs for mental health promotion

Who Benefits Most? Interactions between Personality Traits and Outcomes of Four Incremental Meditation and Yoga Treatments

Cognitive-behavioural therapy and personalized treatment: An introduction to the special issue

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