Adaptor molecules mediate negative regulation of macrophage inflammatory pathways: a closer look
Mirza S. Baig,
Spyridoula Barmpoutsi,
Shreya Bharti
et al.
Abstract:Macrophages play a central role in initiating, maintaining, and terminating inflammation. For that, macrophages respond to various external stimuli in changing environments through signaling pathways that are tightly regulated and interconnected. This process involves, among others, autoregulatory loops that activate and deactivate macrophages through various cytokines, stimulants, and other chemical mediators. Adaptor proteins play an indispensable role in facilitating various inflammatory signals. These prot… Show more
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