Adaptive trials in stroke: Current use & future directions
Kathryn S Hayward,
Emily J Dalton,
Bruce CV Campbell
et al.
Abstract:Inclusion of adaptive design features in a clinical trial provides pre-planned flexibility to dynamically modify a trial during its conduct, while preserving validity and integrity. Adaptive trials are needed to accelerate the conduct of more efficient, informative, and ethical clinical research in the field of neurology as compared to traditional fixed designs. Stroke is a natural candidate for adoption of these innovative approaches to trial design. This Research Methods in Neurology paper is informed by sco… Show more
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