Adaptive strategies of Listeria monocytogenes : Evolved variants with altered stress resistance and fitness

Abstract

Ribosomal mutations enable a switch between high fitness and high stress resistance in Listeria monocytogenes 3 A single point mutation in the Listeria monocytogenes ribosomal gene rpsU enables SigB activation independently of the stressosome and the anti-sigma factor antagonist RsbV 4 Stress resistant rpsU variants of Listeria monocytogenes can become underrepresented due to enrichment bias 5 Activation of a silent lactose utilization pathway in an evolved Listeria monocytogenes F2365 outbreak isolate