Adaptive optics visual simulators: a review of recent optical designs and applications [Invited]

Marcos, Susana; Artal, Pablo; Atchison, David A.; Hampson, Karen M.; Legras, Richard; Lundström, Linda; Yoon, Geunyoung

doi:10.1364/boe.473458

Cited by 8 publications

(3 citation statements)

References 121 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Plasticity of the lens growth shells allows for subtle improvements in the optical properties as eyes grow from youth to adult ( 16 , 96 , 97 ). Developmentally, dramatic plasticity is demonstrated in lens inversion experiments ( 98 , 99 ).…”

Section: Growth Shellsmentioning

confidence: 99%

The significance of growth shells in development of symmetry, transparency, and refraction of the human lens

Greiling,

Clark,

Clark

2024

Front. Ophthalmol.

View full text Add to dashboard Cite

Human visual function depends on the biological lens, a biconvex optical element formed by coordinated, synchronous generation of growth shells produced from ordered cells at the lens equator, the distal edge of the epithelium. Growth shells are comprised of straight (St) and S-shaped (SSh) lens fibers organized in highly symmetric, sinusoidal pattern which optimizes both the refractile, transparent structure and the unique microcirculation that regulates hydration and nutrition over the lifetime of an individual. The fiber cells are characterized by diversity in composition and age. All fiber cells remain interconnected in their growth shells throughout the life of the adult lens. As an optical element, cellular differentiation is constrained by the physical properties of light and its special development accounts for its characteristic symmetry, gradient of refractive index (GRIN), short range transparent order (SRO), and functional longevity. The complex sinusoidal structure is the basis for the lens microcirculation required for the establishment and maintenance of image formation.

show abstract

Section: Growth Shellsmentioning

confidence: 99%

The significance of growth shells in development of symmetry, transparency, and refraction of the human lens

Greiling,

Clark,

Clark

2024

Front. Ophthalmol.

View full text Add to dashboard Cite

show abstract

“…Binocular vision simulators 17 – 19 allow the presentation of monovision corrections. The SimVis Gekko is a head-mounted see-through binocular simultaneous vision simulator that uses tunable lenses (which mimic spherical or multifocal corrections) 23 projected onto the eye's pupil plane, allowing a noninvasive and rapid switching of the near add between the eyes without magnification differences.…”

Section: Introductionmentioning

confidence: 99%

Monovision Correction Preference and Eye Dominance Measurements

Rodríguez-López

Barcala

Zaytouny

et al. 2023

Trans. Vis. Sci. Tech.

Self Cite

View full text Add to dashboard Cite

Purpose To propose new methods for eye selection in presbyopic monovision corrections. Methods Twenty subjects with presbyopia performed two standard methods of binary eye dominance identification (sensory with +1.50 diopters [D ]and +0.50 D and sighting with “hole-in-the-card”) and two psychophysical methods of perceived visual quality: (1) the Preferential test, 26 natural images were judged with the near addition in one eye or in the other in a 2-interval forced-choice task, and the Eye Dominance Strength (EDS) defined as the proportion of trials where one monovision is preferred over the other; (2) the Multifocal Acceptance Score (MAS-2EV) test, the perceived quality of a natural images set (for 2 luminance levels and distances) was scored and EDS defined as the score difference between monovision in one eye or the other. Left-eye and right-eye dominance are indicated with negative and positive values, respectively. Tests were performed using a Simultaneous Vision Simulator, which allows rapid changes between corrections. Results Standard sensory and sighting dominances matched in only 55% of subjects. The Preferential EDS (ranging from −0.7 to +0.9) and MAS-2EV EDS (ranging from −0.6 to +0.4) were highly correlated. Selecting the eye for far in monovision with the MAS-2EV, sensory, or sighting tests would have resulted in 79%, 64%, and 43% success considering the Preferential test as the gold standard. Conclusions Tests based on perceptual preference allow selection of the preferred monovision correction and measurement of dominance strength. Translational Relevance The binocular visual simulator allows efficient implementation of eye preference tests for monovision in clinical use.

show abstract

“…It also includes the realistic correction of aberrations and vision perception through any defined aberration profile [5][6][7][8] . The AO visual simulators involve the objective evaluation of ocular aberrations through wavefront sensing (i.e., Hartmann-Shack sensor) and subjective visual testing through manipulation of aberrations using wavefront shaping components [9][10][11] . However, one of the major limitations of the existing AO visual simulators is the size and immobility.…”

Section: Introductionmentioning

confidence: 99%

A handheld adaptive optics device for personalized visual evaluation

Soomro

Artal²

2023

Ophthalmic Technologies XXXIII

Self Cite

View full text Add to dashboard Cite

Visual simulation is an emerging technology used in ophthalmology where a subject sees through manipulated optical conditions. The existing visual simulation tools are quite advanced and trailblazing. However, they cannot follow the miniaturization and mobility trends of the technology. Current visual simulators are bulky in size and require a tabletop arrangement for operation. Here we propose a novel handheld and portable adaptive optics visual simulator that can induce a variety of optical corrections and measure ocular aberrations in real-time while realizing the form-factor similar to the typical virtual reality headsets. The proposed device has two main parts: a wavefront shaping module for manipulation of visual stimuli and a wavefront sensing module for evaluation of ocular aberrations, which are integrated into a standalone handheld unit. The device incorporates a micro-display and a liquid crystal-on silicon (LCOS) phase modulator for wavefront shaping combined with a Hartmann-Shack (HS) wavefront sensor. Our prototype device incorporates miniature optical components and a path folding mechanism combined with in-house 3D printed mounts and covers to reduce the device footprints. The prototype device is tested by inducing the known values of defocus and astigmatism through a set of trial lenses, measuring the induced aberrations, and evaluating the simulated corrections. Our results show high measurement accuracy (R2>0.999) when tested on spherical and cylindrical trial lenses ranging from -10 to 10 diopters and -5 to 5 diopters, respectively. The visual correction performance shows better than 20/20 visual acuity resolution for the defocus correction of -5 to 5 diopters.

show abstract

Adaptive optics visual simulators: a review of recent optical designs and applications [Invited]

Cited by 8 publications

References 121 publications

The significance of growth shells in development of symmetry, transparency, and refraction of the human lens

The significance of growth shells in development of symmetry, transparency, and refraction of the human lens

Monovision Correction Preference and Eye Dominance Measurements

A handheld adaptive optics device for personalized visual evaluation

Contact Info

Product

Resources

About