Adaptive handling of Rayleigh and Raman scatter of fluorescence data based on evaluation of the degree of spectral overlap

Hu, Yingtian; Liu, Chao; Wang, Xiaoping; Zhao, Dongdong

doi:10.1016/j.saa.2018.03.058

Cited by 8 publications

(3 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In most instances, the generation of a single Raman photon necessitates the incidence of approximately 10 6 –10 8 laser photons upon the sample [ 89 , 90 ]. Consequently, even minute concentrations of fluorescent species (either in pure compound or as interferences) within the sample can obscure or complicate the detection and interpretation of the weak Raman-scattered photon signals [ 91 , 92 ]. If the fluorescence baseline is elevated, the shot noise emanating from this signal may equate to or even surpass the intensity of the Raman signal itself, effectively veiling the Raman photon signals [ 91 , 93 ].…”

Section: Resultsmentioning

confidence: 99%

“…While the spect for the initial reagent, 7-methoxy-1-tetralone, was clear with minimum noise, it is im ative to acknowledge the inherent inefficiency of Raman scattering, particularly in the text of fluorescent compounds such as the developed 7′-Methoxy-[1,1′-binaphthalen]-In most instances, the generation of a single Raman photon necessitates the inciden approximately 10 6 -10 8 laser photons upon the sample [89,90]. Consequently, even mi concentrations of fluorescent species (either in pure compound or as interferences) w the sample can obscure or complicate the detection and interpretation of the weak Ram scattered photon signals [91,92]. If the fluorescence baseline is elevated, the shot noise anating from this signal may equate to or even surpass the intensity of the Raman si itself, effectively veiling the Raman photon signals [91,93].…”

Section: Raman Spectroscopymentioning

confidence: 99%

See 1 more Smart Citation

Unveiling Morphine: A Rapid and Selective Fluorescence Sensor for Forensic and Medical Analysis

Boroujerdi,

Butt,

Paul

et al. 2024

Sensors

View full text Add to dashboard Cite

Opioid use, particularly morphine, is linked to CNS-related disorders, comorbidities, and premature death. Morphine, a widely abused opioid, poses a significant global health threat and serves as a key metabolite in various opioids. Here, we present a turn-off fluorescent sensor capable of detecting morphine with exceptional sensitivity and speed in various samples. The fluorescent sensor was developed through the dimerization process of 7-methoxy-1-tetralone and subsequent demethylation to produce the final product. Despite morphine possessing inherent fluorophoric properties and emitting light in an approximately similar wavelength as the sensor’s fluorescent blue light, the introduction of the target molecule (morphine) in the presence of the sensor caused a reduction in the sensor’s fluorescence intensity, which is attributable to the formation of the sensor–morphine complex. By utilizing this fluorescence quenching sensor, the chemo-selective detection of morphine becomes highly feasible, encompassing a linear range from 0.008 to 40 ppm with an impressive limit of detection of 8 ppb. Consequently, this molecular probe demonstrates a successful application in determining trace amounts of morphine within urine, yielding satisfactory analytical results. The study also explores the effect of several variables on the sensor’s response and optimizes the detection of morphine in urine using a response surface methodology with a central composite design.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Raman Spectroscopymentioning

confidence: 99%

Unveiling Morphine: A Rapid and Selective Fluorescence Sensor for Forensic and Medical Analysis

Boroujerdi,

Butt,

Paul

et al. 2024

Sensors

View full text Add to dashboard Cite

show abstract

“…Figure 1 a,b reveal that fluorescence peaks arose at 413 nm in the experimental group, the physical mixture of DASPI and the four crystal types of starches, and DASPI. However, this is a Raman scattering peak induced by the bending and vibration of the solvent water molecules [ 17 ] and not a DASPI dye peak. The DASPI dye emits fluorescence at 585 nm under 365 nm excitation wavelengths.…”

Section: Resultsmentioning

confidence: 99%

The Fluorescence Response of Four Crystalline Starches According to Ultrasound-Assisted Starch-Salicylic Acid Inclusions

Pei

Wang

et al. 2023

Foods

View full text Add to dashboard Cite

Fluorescence has shown its superior performance in the fields of starch physicochemical properties, starch–based materials, and the interactions of starch with small molecules. However, it has not been well explored in the fluorescence characteristics of starch. Herein, the fluorescence properties of four crystalline starches (A–type tapioca starch, B–type potato starch, C–type pea starch, and V–type starch, prepared with corn starch and stearic acid) were investigated using salicylic acid (SA) as an indicator. The results of inverted fluorescence microscopy, Fourier transform infrared spectroscopy, and thermogravimetric analysis indicated that SA could be included by starch. X–ray diffraction analysis further demonstrated that the inclusion of SA did not change the crystalline of the four crystal types of starches, which could provide a prerequisite for comparing the different fluorescence properties of the four crystal types of starches. Fluorescence enhancements of the four inclusions were 264.5 (B–type), 206 (C–type), 51.2 (V–type), and 28 (A–type). These results provide new insights for analyzing the fluorescence response of starch.

show abstract

Effects of microbubble pretreatment on physiochemical and microbial properties of excess activated sludge

Zhou,

Yu,

Zeng

et al. 2024

Environ Sci Pollut Res

View full text Add to dashboard Cite

Adaptive handling of Rayleigh and Raman scatter of fluorescence data based on evaluation of the degree of spectral overlap

Cited by 8 publications

References 17 publications

Unveiling Morphine: A Rapid and Selective Fluorescence Sensor for Forensic and Medical Analysis

Unveiling Morphine: A Rapid and Selective Fluorescence Sensor for Forensic and Medical Analysis

The Fluorescence Response of Four Crystalline Starches According to Ultrasound-Assisted Starch-Salicylic Acid Inclusions

Effects of microbubble pretreatment on physiochemical and microbial properties of excess activated sludge

Contact Info

Product

Resources

About