Adaptive Changes in Rats Exposed to Cold. Caloric Exchange

Cottle, W. H.; Carlson, Loren D.

doi:10.1152/ajplegacy.1954.178.2.305

Cited by 58 publications

(17 citation statements)

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“…In rodents, acclimatization involves physiological changes resulting in an increased capacity for energy metabolism (Gelineo, 1934;Cottle and Carlson, 1954;Depocas, Hart and Heroux, 1957). The physiological data of Sykes andSlee (1968, 1969b) suggest that in sheep also there were increases in basal metabolism and in summit metabolic capability after acclimatization.…”

Section: Introductionmentioning

confidence: 99%

Cold exposure of Southdown and Welsh Mountain sheep. 4. Changes in concentrations of free fatty acids, glucose, acetone, protein-bound iodine, protein and antibody in the blood

Halliday¹,

Ar²,

Slee³

et al. 1969

Anim. Sci.

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Twenty-four Southdown and 24Welsh Mountain year-old female sheep, half on high-plane and half on low-plane nutrition, were shorn and given two acute cold exposures in climate chambers. For 2 weeks before and 2 weeks between exposures the sheep were kept in a subcritical (4-8°C) or a thermoneutral (+30°C) environment. Before the temperature treatment each sheep received an injection of Brucella abortus vaccine. Blood samples were taken during exposure to + 8°C and + 30°C and during the acute cold exposures for estimation of free fatty acid (FFA), protein-bound iodine (PBI), glucose, acetone, serum protein and antibody levels. FFA and glucose levels alone were measured in 32 similarly treated Scottish Blackface sheep. 1. Low plane sheep had higher PBI levels at all temperatures, and higher glucose levels during acute cold exposure than high plane sheep. Otherwise most major effects were attributable to ambient temperature. 2. At +8°C the PBI, FFA, glucose, serum protein and acetone levels were higher than at + 30°C. 3. Blackface sheep had lower FFA and glucose levels than Southdown and Welsh sheep at both temperatures. 4. During acute cold exposure, PBI, acetone and FFA levels increased further. PBI levels were highest in sheep previously at + 30 c C, and acetone highest in sheep previously at + 8°C. Very high FFA levels were recorded, especially in sheep not previously coldacclimatized. 5. Glucose levels increased initially, but fell towards the end of acute exposure, suggesting that relatively less carbohydrate and more fat was utilized for energy metabolism during this period. t Present address: Moredun Research Institute, Edinburgh 9. 479 ANIM. PROD.-VOL. 11, PT. 4 4 8 0 HALLIDAY, SYKES, SLEE, FIELD AND RUSSEL6. Serum protein levels fell during acute exposure, possibly because protein catabolism increased. The proportions of albumin and y-globulin increased and decreased respectively. 7. No effects of temperature on antibody levels were detected.

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Section: Introductionmentioning

confidence: 99%

Cold exposure of Southdown and Welsh Mountain sheep. 4. Changes in concentrations of free fatty acids, glucose, acetone, protein-bound iodine, protein and antibody in the blood

Halliday¹,

Ar²,

Slee³

et al. 1969

Anim. Sci.

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show abstract

“…The conclusion may be drawn that younger rats can Increase their food intake to meet the increased metabolic requirement while the older rats are much less able to adjust. That growth Is slowed by cold even though rats in the cold consume much more food has been noted by several investigators (13,14,15,16,17). Heroux (14) Illustrated that the mltotic activity In the ear epidermis was almost completely arrested for the first 21 to 28 days in the cold.…”

Section: Discussionmentioning

confidence: 78%

The Effect of Acclimatization to Cold on the G Tolerance of Rats

Reeves¹

1961

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“…In the cold exposures reported here, the temperature was not so extreme that there was a loss of weight but the gain was less than that of the controls. Loss of weight on exposure to cold was reported by Katsh, Katsh, and Osher (1954); Cottle and Carlson (1954), Dugal and Therien (1949), and Leblond and Gross (1943) are among those who have reported lower weight gain on exposure to cold.…”

Section: Discussionmentioning

confidence: 90%

Effect of extremes of temperature and humidity on the goblet cell count in the rat airway epithelium

Jones

Baetjer

Reid

1971

Occupational and Environmental Medicine

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. (1971). Brit. J. industr. Med., 28, 369-373. Effect of extremes of temperature and humidity on the goblet cell count in the rat airway epithelium. To investigate the effect of environmental temperature and humidity on the goblet cells in the rat airway epithelium, eight animals were exposed for four to five weeks to each of the following conditions: normal; hot-moist or tropical; hot-dry or desert; and cold. The animals in the three groups exposed to abnormal atmospheric conditions failed to gain weight as fast as those in the control group. No increase in the number or area of goblet cells was found in any group, although with irritants previously tested, such as tobacco smoke, a marked increase has been found in this time. It would seem that climatic effects are much less important than irritation in the production of hypertrophy and hyperplasia of mucus-secreting cells, the hallmark of chronic bronchitis.

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Adaptive Changes in Rats Exposed to Cold. Caloric Exchange

Cited by 58 publications

References 0 publications

Cold exposure of Southdown and Welsh Mountain sheep. 4. Changes in concentrations of free fatty acids, glucose, acetone, protein-bound iodine, protein and antibody in the blood

Cold exposure of Southdown and Welsh Mountain sheep. 4. Changes in concentrations of free fatty acids, glucose, acetone, protein-bound iodine, protein and antibody in the blood

The Effect of Acclimatization to Cold on the G Tolerance of Rats

Effect of extremes of temperature and humidity on the goblet cell count in the rat airway epithelium

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