“…Golgi fragmentation occurs in pathological situations, such as when apoptosis is activated and when vesicular secretory trafficking is perturbed [ 21 , 47 , 48 , 49 , 50 , 51 , 52 ]. Furthermore, several evidences show that the Golgi apparatus plays a key role in sensing and integrating external and intracellular cues to promote cellular homeostasis [ 53 , 54 ]. Similarly, from what we observed, mice lacking the fukutin gene (Fktn), the causative gene of Fukuyama muscular dystrophy, show myocyte contractile dysfunction and a disordered Golgi network [ 55 ].…”