Adaptation ofPseudomonas aeruginosato repeated invasion into a commensal competitor
Rachel M. Wheatley,
Liam P. Shaw,
Sarah Shah
et al.
Abstract:The host-associated microbiome is an important barrier to bacterial pathogen colonization and can mediate protection through a variety of mechanisms. We wanted to investigate the potential consequences of selection imposed by commensal bacterial competitors on an invading bacterial pathogen. To do this, we tested the ability of the opportunistic pathogenPseudomonas aeruginosato invade pre-established communities of an abundant commensal bacterium in the human microbiome,Staphylococcus epidermidis. We passaged … Show more
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