Adaptation of biological membranes to temperature. The lack of homeoviscous adaptation in the sarcoplasmic reticulum

Cossins, Andrew R.; Christiansen, James A.; Prosser, C. Ladd

doi:10.1016/0005-2736(78)90280-8

Cited by 63 publications

(15 citation statements)

References 21 publications

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“…It has been noted that membranes from cold-acclimated/adapted ectotherms are generally enriched in unsaturated fatty acids and also that homeoviscous efficacy is typically higher in mitochondrial membranes than other membrane fractions. Although UI are similar for mitochondria from cold-and warm-acclimated killifish (Table1), mitochondria from killifish at 5°C are significantly enriched in phospholipids containing highly unsaturated fatty acids such as PE killifish over the acclimatory period, adding to a growing body of literature that indicates clearly that phospholipid compositions of microsomal and SR membranes are less affected by temperature change (Cossins et al, 1978;Vornanen et al, 1999).…”

Section: Temperature-induced Membrane Remodelingmentioning

confidence: 89%

Temperature acclimation alters oxidative capacities and composition of membrane lipids without influencing activities of enzymatic antioxidants or susceptibility to lipid peroxidation in fish muscle

Grim

Miles

Crockett

2010

Journal of Experimental Biology

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SUMMARYCold acclimation of ectotherms results typically in enhanced oxidative capacities and lipid remodeling, changes that should increase the risk of lipid peroxidation (LPO). It is unclear whether activities of antioxidant enzymes may respond in a manner to mitigate the increased potential for LPO. The current study addresses these questions using killifish (Fundulus heteroclitus macrolepidotus) and bluegill (Lepomis macrochirus) acclimated to 5 and 25°C for 9days and 2months, respectively. Because the effects of temperature acclimation on pro-and antioxidant metabolism may be confounded by variable activity levels among temperature groups, one species (killifish) was also subjected to a 9-day exercise acclimation. Oxidative capacity of glycolytic (skeletal) muscle (indicated by the activity of cytochrome c oxidase) was elevated by 1.5-fold in killifish, following cold acclimation, but was unchanged in cardiac muscle and also unaffected by exercise acclimation in either tissue. No changes in citrate synthase activity were detected in either tissue following temperature acclimation. Enzymatic antioxidants (catalase and superoxide dismutase) of either muscle type were unaltered by temperature or exercise acclimation. Mitochondria from glycolytic muscle of cold-acclimated killifish were enriched in highly oxidizable polyunsatured fatty acids (PUFA), including diacyl phospholipids (total carbons:total double bonds) 40:8 and 44:12. Increased oxidative capacity, coupled with elevated PUFA content in mitochondria from cold-acclimated animals did not, however, impact LPO susceptibility when measured with C11-BODIPY. The apparent mismatch between oxidative capacity and enzymatic antioxidants following temperature acclimation will be addressed in future studies.

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Section: Temperature-induced Membrane Remodelingmentioning

confidence: 89%

Temperature acclimation alters oxidative capacities and composition of membrane lipids without influencing activities of enzymatic antioxidants or susceptibility to lipid peroxidation in fish muscle

Grim

Miles

Crockett

2010

Journal of Experimental Biology

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“…e$cacies of less than 100% are not uncommon). For example, the sarcoplasmic reticulum does not show homeoviscous adaptation (Cossins et al, 1978).…”

Section: The Fluid Membrane Bilayermentioning

confidence: 99%

Membranes as Possible Pacemakers of Metabolism

Hulbert

Else

1999

Journal of Theoretical Biology

278

190

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“…According to Porter et al [74] , proton leak increases as a function of inner mitochondrial membrane surface area (cristae density) and can be modulated by the degree of unsaturated fatty acids in the membrane. Higher numbers of mitochondria and higher cristae densities are found in coldadapted ectotherms, and these help to overcome diffusion problems and compensate for the decline in metabolism at cold temperatures [75] . A comparison of the cytochrome-c oxidase/citrate synthase activity ratio in temperate and polar mud clams indeed suggests the polar species to have higher mitochondrial cristae densities [24] .…”

Section: Polar Longevitymentioning

confidence: 99%

Masters of Longevity: Lessons from Long-Lived Bivalves – A Mini-Review

2009

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The individual ages of bivalve molluscs can be inferred from the age rings laid down every year in the shell, especially in species inhabiting areas with seasonal variability in environmental factors such as food supply and temperature. Animals obtained from different environmental settings can therefore be used to investigate how specific environmental factors shape the process of ageing in this animal class. Some bivalves have extraordinary long life spans. Species like the ocean quahog Arctica islandica and the freshwater pearl mussel Margaritifera margaritifera live for over hundreds of years. Few studies so far have attempted to study the process of ageing, either specifically in long-lived bivalves or generally in very long-lived species. This review summarizes the current knowledge of cellular ageing in bivalves with a focus on the antioxidant system, as well as tissue repair and metabolic capacities of extremely long-lived species. We discuss the applicability of these animals as models for different ageing theories. We recommend a focus of future research on the molecular mechanisms potentially involved in supporting longevity in these species, including evolutionary old cellular mechanisms such as autophagy and apoptosis, as well as diverse cellular repair pathways.

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Adaptation of biological membranes to temperature. The lack of homeoviscous adaptation in the sarcoplasmic reticulum

Cited by 63 publications

References 21 publications

Temperature acclimation alters oxidative capacities and composition of membrane lipids without influencing activities of enzymatic antioxidants or susceptibility to lipid peroxidation in fish muscle

Temperature acclimation alters oxidative capacities and composition of membrane lipids without influencing activities of enzymatic antioxidants or susceptibility to lipid peroxidation in fish muscle

Membranes as Possible Pacemakers of Metabolism

Masters of Longevity: Lessons from Long-Lived Bivalves – A Mini-Review

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