Adaptation and Dissemination of Korean Medicine Clinical Practice Guidelines for Traffic Injuries

Lim, Kyeong-Tae; Kim, Hyun-Tae; Hwang, Eui-Hyoung; Hwang, Man-Suk; Heo, In; Park, Sunyoung; Cho, Jae-Heung; Kim, Koh-Woon; Ha, In‐Hyuk; Kim, Me-riong; Park, Kyoung-Sun; Kang, Hyung Won; Lee, Jun-Hwan; Shin, Byung‐Cheul

doi:10.3390/healthcare10071166

Cited by 3 publications

(3 citation statements)

References 16 publications

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“…A survival analysis was performed based on the definition of recovery as a decrease in the NRS score by ≥50%. The median times to recover measured within 91 days were 41 days (36)(37)(38)(39)(40)(41)(42)(43) after randomization in the PL-MSAT group and 41 days (40-46) after randomization in the control group. The values of the log-rank test statistic and hazard ratio were 0.20 and 1.28 (0.89-1.96), respectively, at 91 days, showing no statistically significant between-group differences (Table 6).…”

Section: Survival Analysismentioning

confidence: 99%

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Effectiveness and Safety of Progressive Loading–Motion Style Acupuncture Treatment for Acute Low Back Pain after Traffic Accidents: A Randomized Controlled Trial

Hwangbo,

Kim,

Shin

et al. 2023

Healthcare

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Background: Traffic injuries include acute low back pain (LBP) needing active treatment to prevent chronicity. This two-armed, parallel, assessor-blinded, randomized controlled trial evaluated the effectiveness and safety of progressive loading–motion style acupuncture treatment (PL-MSAT) for acute LBP following traffic accidents. Methods: Based on an effect size of 1.03, 104 participants were recruited and divided in a 1:1 ratio into PL-MAST and control groups using block randomization. Both groups underwent integrative Korean medicine treatment (IKMT) daily; only the PL-MSAT group underwent three PL-MSAT sessions. The outcomes were assessed before and after the treatment sessions and at 1 and 3 months post-discharge. The primary outcome was the difference in the numeric rating scale (NRS) for LBP. The secondary outcomes included a visual analog scale for LBP, leg pain status, the Oswestry disability index, lumbar active range of motion (ROM), quality of life, Patient Global Impression of Change, and Post-Traumatic Stress Disorder Checklist adverse events. Results: In the modified intention-to-treat analysis, 50 and 51 participants were included in the PL-MSAT and control groups. On Day 4, the mean LBP NRS score was 3.67 (3.44–3.90) in the PL-MSAT group, indicating a significantly lower NRS 0.77 (0.44–1.11) compared to 4.44 (4.20–4.68) for the control group (p < 0.001). The PL-MSAT group exhibited greater ROM flexion (−5.31; −8.15 to −2.48) and extension (−2.09; −3.39 to −0.80). No significant differences were found for the secondary outcomes and follow-ups. Conclusions: Compared with IKMT alone, PL-MSAT plus IKMT showed significantly better outcomes for reducing pain and increasing the ROM in acute LBP.

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Section: Survival Analysismentioning

confidence: 99%

“…Second, this study used IKMT, which is commonly used for the treatment of LBP after TAs in current clinical practice [37], as a control intervention. Thus, the effect size may have been small compared with cases where a different treatment method was used as the control intervention.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

Effectiveness and Safety of Progressive Loading–Motion Style Acupuncture Treatment for Acute Low Back Pain after Traffic Accidents: A Randomized Controlled Trial

Hwangbo,

Kim,

Shin

et al. 2023

Healthcare

Self Cite

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“…The conventional approaches used for HF recommendation systems mainly rely on expert knowledge. The majority of these conventional approaches are clinical practice guidelines that collect diagnostic criteria and determine administrable HFs based on expert consensus or questionnaires that can classify pathological patterns or formula indications [ 6 , 7 , 8 ]. These approaches can act as indirect guides in clinical practice, but they cannot directly assist in the process of HF selection for individual patients.…”

Section: Introductionmentioning

confidence: 99%

A Machine Learning Approach for Recommending Herbal Formulae with Enhanced Interpretability and Applicability

Lee

et al. 2022

Biomolecules

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Herbal formulae (HFs) are representative interventions in Korean medicine (KM) for the prevention and treatment of various diseases. Here, we proposed a machine learning-based approach for HF recommendation with enhanced interpretability and applicability. A dataset consisting of clinical symptoms, Sasang constitution (SC) types, and prescribed HFs was derived from a multicenter study. Case studies published over 10 years were collected and curated by experts. Various classifiers, oversampling methods, and data imputation techniques were comprehensively considered. The local interpretable model-agnostic explanation (LIME) technique was applied to identify the clinical symptoms that led to the recommendation of specific HFs. We found that the cascaded deep forest (CDF) model with data imputation and oversampling yielded the best performance on the training set and holdout test set. Our model also achieved top-1 and top-3 accuracies of 0.35 and 0.89, respectively, on case study datasets in which clinical symptoms were only partially recorded. We performed an expert evaluation on the reliability of interpretation results using case studies and achieved a score close to normal. Taken together, our model will contribute to the modernization of KM and the identification of an HF selection process through the development of a practically useful HF recommendation model.

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Efficacy and Safety of Korean Herbal Medicine for Patients with Post-Accident Syndrome, Persistent after Acute Phase: A Pragmatic Randomized Controlled Trial

Hwang

Park

et al. 2023

Healthcare

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This is a pragmatic, two-armed, parallel, single-center, randomized controlled clinical trial for comparative evaluation between the effectiveness of integrated Korean medicine (IKM) and herbal medicine treatment with that of IKM monotherapy (control) for post-accident syndrome persistent after the acute phase. Participants were randomized into Herbal Medicine (HM, n = 20) and Control groups (n = 20) to receive the allocated treatment of 1–3 sessions/week for 4 weeks. Intention-to-treat analysis was conducted. The Difference of Numeric Rating Scale (NRS) change of overall post-accident syndromes from baseline to week 5 for the two groups was 1.78 (95% CI: 1.08–2.48; p < 0.001). Regarding secondary outcomes, a significant decrease compared to the baseline values was confirmed for NRS of musculoskeletal, neurological, psychiatric complaints and general symptoms of post-accident syndromes. In a survival analysis based on the recovery criteria of “patients with a reduction in the NRS of overall post-accident syndromes of ≥50%,” the HM group showed a shorter time to recovery than the control group during the 17-week study period (p < 0.001 by the log-rank test). IKM combined with herbal medicine treatment significantly improved the quality of life by relieving somatic pain and alleviating the overall post-accident syndrome persistent after the acute phase; this effect was maintained for at least 17 weeks.

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Adaptation and Dissemination of Korean Medicine Clinical Practice Guidelines for Traffic Injuries

Cited by 3 publications

References 16 publications

Effectiveness and Safety of Progressive Loading–Motion Style Acupuncture Treatment for Acute Low Back Pain after Traffic Accidents: A Randomized Controlled Trial

Effectiveness and Safety of Progressive Loading–Motion Style Acupuncture Treatment for Acute Low Back Pain after Traffic Accidents: A Randomized Controlled Trial

A Machine Learning Approach for Recommending Herbal Formulae with Enhanced Interpretability and Applicability

Efficacy and Safety of Korean Herbal Medicine for Patients with Post-Accident Syndrome, Persistent after Acute Phase: A Pragmatic Randomized Controlled Trial

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