Adaptable and Automated Rodent Behavior Maze System

Abstract

Mazes are a fundamental and widespread tool in behavior and systems neuroscience research in rodents. However, their form and inflexibility often restrict potential experimental paradigms that involve multiple or adaptive maze designs. Unique layouts often cost substantial engineering and time investments from trainee scientists. To alleviate these issues, we have developed an automated modular maze system that is flexible and scalable. This system will allow for experiments with multiple track configurations in rapid succession. Additionally, the flexibility can expedite prototyping of behaviors. Finally, the standardized componentry enhances experimental reproducibility and repeatability. This maze system presents advantages over current maze options and can facilitate novel behavior and systems neuroscience research.

Protocol for geometric transformation of cognitive maps for generalization across hippocampal-prefrontal circuits

“…Xometry ( www.xometry.com ) has been previously used to manufacture custom maze parts for adaptable mazes that are currently used in the laboratory. 3 Note: Instructions for the fabrication of track bases are not covered in this protocol, as appropriate track height may differ between laboratory setups based on the height of various recording equipment. Reward well fabrication and assembly.…”

“…Xometry ( www.xometry.com ) has been previously used to manufacture custom maze parts for adaptable mazes that are currently used in the laboratory. 3 …”