Adams‐Stokes Attacks caused by Ventricular Fibrillation. In a Man with otherwise normal Heart

Storstein, O

doi:10.1111/j.0954-6820.1949.tb09547.x

Cited by 25 publications

(6 citation statements)

References 2 publications

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“…21 ScPVCs were previously reported as an R-on-T phenomenon often initiating VF and described with different names in patients with apparently normal hearts. [12][13][14][15][16] The role of ScPVCs as a specific subset of IVF has been reported with an incidence varying from 6.6% 16 to 20%, 27 depending on the respective inclusion criteria. This arrhythmia was demonstrated to be responsive to quinidine.…”

Section: Short-coupled Ectopy and Scbsmentioning

confidence: 99%

“…5 Over the past decade, specific subtypes of IVF have been described. These were based on phenotypic characterization of the arrhythmia itself, for example, VF initiated by shortcoupled premature ventricular complexes (ScPVCs) [12][13][14][15][16] or based on the presence of subclinical myocardial alterations. 17 ScPVCs originating from the Purkinje system are the most common triggers of IVF and an effective ablation target for preventing VF recurrence.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Malignant Purkinje ectopy induced by sodium channel blockers

Escande¹,

Gourraud²,

Haı̈ssaguerre³

et al. 2022

Heart Rhythm

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Section: Short-coupled Ectopy and Scbsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Malignant Purkinje ectopy induced by sodium channel blockers

Escande¹,

Gourraud²,

Haı̈ssaguerre³

et al. 2022

Heart Rhythm

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“…1 It is well established that a subset of IVF are triggered by short-coupled premature ventricular complexes (PVCs) falling on the T wave (the so-called R-on-T phenomenon), mostly originating from the Purkinje system. [2][3][4][5] In prior studies it was however shown that IVF can also be triggered by PVCs with longer coupling intervals, with an estimation of 17% of cases in a recent review. 4,[6][7][8] Little is known about the presence and site of origin of long-coupled premature ventricular complexes (LCPVCs) in IVF patients.…”

Section: Introductionmentioning

confidence: 99%

“…Idiopathic ventricular fibrillation (IVF) is a major cause of sudden cardiac death (SCD) in young patients without structural or electrical heart disease 1 . It is well established that a subset of IVF are triggered by short‐coupled premature ventricular complexes (PVCs) falling on the T wave (the so‐called R‐on‐T phenomenon), mostly originating from the Purkinje system 2–5 . In prior studies it was however shown that IVF can also be triggered by PVCs with longer coupling intervals, with an estimation of 17% of cases in a recent review 4,6–8 .…”

Section: Introductionmentioning

confidence: 99%

Idiopathic ventricular fibrillation associated with long‐coupled Purkinje ectopy

Surget

Duchâteau

Marchant

et al. 2023

Cardiovasc electrophysiol

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Introduction: Idiopathic ventricular fibrillation (IVF) is mainly associated with and triggered by short-coupled (R-on-T) ventricular ectopics. However, little is known about the risk of VF associated with long-coupled premature ventricular complexes (LCPVCs).Objective: To examine the prevalence and characteristics of IVF patients presenting with LCPVCs.Methods: Consecutive patients with IVF and PVCs from five arrhythmia referral centers were reviewed. We included patients presenting LCPVCs, defined as PVCs falling after the end of the T wave, with a normal QTc interval. We evaluated demographics, medical history, and clinical circumstances associated with PVCs and VF episodes. The origin of PVCs was determined by invasive mapping.Results: Seventy-nine patients with IVF were reviewed. Among them, 12 (15.2%) met the inclusion criteria (8 women, age 36 ± 14 years). Eleven patients had documented LCPVCs initiating repetitive PVCs or sustained VF, whereas 1 had only documented isolated PVCs. In 10 of 12 patients, PVCs were recorded showing both long and short coupling intervals of 418 ± 46 and 304 ± 33 ms, respectively. Mapping showed that PVCs originated from the left Purkinje in 10 patients, from the right Purkinje in 1 patient, and both in 1 patient. Compared to other patients from the initial cohort, IVF with LCPVCs was associated with a left-sided origin of PVCs (92% in long-coupled IVF vs. 46% of left Purkinje PVCs in short-coupled IVF, p = .004). Conclusion:Long-coupled fascicular PVCs, traditionally recognized as benign, can be associated with IVF in a subset of patients. They can induce IVF by themselves or in association with short-coupled PVCs.

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“…Two more cases of Adams-Stocks attacks due to ventricular fibrillation in patients with apparently normal hearts were reported around the same time. 3,4 PVCs are ubiquitous in the general population. In the Framingham Heart Study, PVCs or more complex ventricular arrhythmias were observed in 12% of participants without coronary artery disease monitored for just 1 hour.…”

Section: Discussionmentioning

confidence: 99%