2008
DOI: 10.1136/thx.2007.086512
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Adalimumab-induced bronchospasm: not a class effect

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Cited by 7 publications
(3 citation statements)
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“…Tumor necrosis factor (TNF) alpha has been implicated in asthmatic airway inflammation. The pathophysiologic mechanisms of asthma induced by anti-TNF-alpha treatment are unknown (3,4). Asthma symptoms appeared after introduction of anti-TNF-α in two patients who did not appear to be predisposed to the disease.…”
Section: Discussionmentioning
confidence: 99%
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“…Tumor necrosis factor (TNF) alpha has been implicated in asthmatic airway inflammation. The pathophysiologic mechanisms of asthma induced by anti-TNF-alpha treatment are unknown (3,4). Asthma symptoms appeared after introduction of anti-TNF-α in two patients who did not appear to be predisposed to the disease.…”
Section: Discussionmentioning
confidence: 99%
“…In most of the adalimumab reported cases the asthma has been mild and adalimumab has not needed to be withdrawn. The details of the asthma adverse events to infliximab and etanercept are not available (1)(2)(3)(4)(5). In the absence of other guidelines, we followed the American Thoracic Society (ATS) guidelines for asthma and added an inhaled steroid, which completely resolved the patient's symptoms but we stopped adalimumab in case (2).…”
Section: Discussionmentioning
confidence: 99%
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