“…Acylimines of hexafluoroacetone serve as synthons for the synthesis of various heterocyclic compounds contain ing geminal trifluoromethyl groups and are used as heterodienes and dienophiles in cycloaddition with ni triles, 1,2 derivatives of trivalent phosphorus acids, 3 and cyclopentadiene 4 as well as 1,3 bielectrophilic reagents in cyclocondensation with 1,3 binucleophiles 5, 6 to give oxadiazines, oxazaphospholenes, azanorbornenes, and dihydrotriazines, respectively. In the present study, we examined the synthetic possibilities of acylimines of hexafluoroacetone 1 as 1,3 bielectrophilic reagents for the preparation of 1,4 dihydropyrimidines by cyclo condensation with 1,3 C,N binucleophiles.…”