Acylation of piperidine and morpholine with phenyl benzoates in the mixtures water-2-propanol and water-dioxane

Abstract

Kinetics of acylation of piperidine and morpholine with 4-nitro-and 2,6-dinitrophenyl benzoates was studied in binary systems water-2-propanol and water-dioxane. Structural and energy characteristics of solvate complexes of morpholine and piperidine with the components of the mixed solvents were calculated. Kinetic regularities of acylation are considered from the viewpoint of specific solvation of amines.