Acylation of 3,4‐Dihydropyrrolo[1,2‐a]pyrazines.

Abstract

Acylation of 3,4-Dihydropyrrolo[1,2-a]pyrazines. -The preparation of new heteroaromatic trifluoromethyl ketones is presented. The direction of trifluoroacetylation depends on the structure of the starting compounds and on the ratio of reagent to substrate. -(TERENIN, V. I.; KABANOVA, E. V.; TSELISHCHEVA, N. A.; KOVALKINA, M. A.; PLESHKOVA, A. P.; ZYK, N. V.; Chem. Heterocycl. Compd. (N. Y.) 40 (2004) 3, 351-360; Lomonosov Moscow State Univ., Moscow 119899, Russia; Eng.) -K. Woydowski 51-135

Chemistry of heterocyclic compounds at the Department of Organic Chemistry, Chemical Faculty, M. V. Lomonosov State University. (Review)

“…[207,208] and dipyrrolo[1,2-a;2',1'-c]pyrazines [209][210][211][212][213][214][215][216] in electrophilic substitution reactions (protonation, acylation, aminomethylation, nitration, formylation, phosphorylation) was investigated systematically. [207,208] and dipyrrolo[1,2-a;2',1'-c]pyrazines [209][210][211][212][213][214][215][216] in electrophilic substitution reactions (protonation, acylation, aminomethylation, nitration, formylation, phosphorylation) was investigated systematically.…”