Acyclic halogen and hydrogen bonding diquat-containing receptors for the electrochemical sensing of anions

Facile and Reliable Emission‐Based Nanomolar Anion Sensing by Luminescent Iridium Receptors Featuring Chelating Halogen‐Bonding Sites

“… Schematic representation of selected bidentate XB receptors based on a) carbazole [8d] and b) bis‐ N ‐alkylated bipyridine, [8b] d, e) luminescent Ir‐based HB sensors based on d) the bpy [19] and e) benzimidazole ligands, [20] c) a luminescent rotaxane based on a strong dicationic XB receptor subunit (bis‐triazolium fragment shown in red) and a weak XB‐based Re sensor subunit, [7b] and f) an Ir‐based bidentate XB sensor (this work).…”

Relationships between hydrogen bonds and halogen bonds in biological systems

“…Interest in halogen bonds (XBs) has seen a revival in the past couple of decades, as the potential to exploit their unique properties has become better recognized (Erdé lyi, 2012;Gilday et al, 2015;Cavallo et al, 2016). XBs are widely applied to the chemical engineering of crystals and supramolecular assemblies (Metrangolo & Resnati, 2001;Metrangolo et al, 2005), including designing liquid crystals (Nguyen et al, 2004;Bruce, 2008;Chen et al, 2014;Fernandez-Palacio et al, 2016), and organometallic frameworks (Maharramov et al, 2016), stabilizing volatile liquids (Aakerö y et al, 2015), synthesizing organic catalysts (Coulembier et al, 2010;Jungbauer & Huber, 2015;Matsuzawa et al, 2016), designing anion receptors (Sarwar, Dragisic, Sagoo et al, 2010;Kilah et al, 2011;Tepper et al, 2015;Amendola et al, 2016;Wageling et al, 2016;Mullaney et al, 2016;Hoque & Das, 2016), and in host-guest assemblies (Dumele et al, 2015;Noa et al, 2015Noa et al, , 2016Gonzá lez et al, 2016;Puttreddy et al, 2016). In biology (Auffinger et al, 2004;Scholfield et al, 2013), XBs are seen to direct DNA macromolecular conformations (Voth, Hays & Ho, 2007), to increase the affinity of agonists (Rohde et al, 2012) and antagonists to protein targets (Lam et al, 2009;Lu, Shi et al, 2009;Hardegger et al, 2011;Scholfield et al, 2013;Xu et al, 2014;…”

A Halogen Bonding 1,3‐Disubstituted Ferrocene Receptor for Recognition and Redox Sensing of Azide

“…[18,19] In recent years, halogen bonding (XB), a supramolecular interaction arising from an electron-deficient halogen atom and a Lewis base, [20] has received increasing attention as a tool for enhancing the selective recognition and sensing of anions in solution. [21][22][23] Very recently, XB motifs have been successfully integrated into redox-active receptor structural frameworks containing ferrocene, [24] diquat [25] and tetrathiafulvalene [26] and were demonstrated to enhance the electrochemical sensing of halides in comparison to HB analogues. Ferrocene, in particular, has been the redox-active motif of choice due to its chemical stability, wide synthetic repertoire, favourable voltammetric properties and facile integration into sensitive electrochemical devices.…”