Acute worsening of dermatomyositis after initiation of PARP inhibitor therapy in two women with advanced ovarian malignancy

Abstract

Highlights Chemotherapy initiation and subsequent tumor lysis can release immunogenic antigens. Advanced staged ovarian cancer associated with dermatomyositis. PARP Inhibitor initiation can worsen paraneoplastic syndromes like dermatomyositis. Signs and symptoms of dermatomyositis can be confused with chemotherapy side-effects.