Acute Toxicity of Daphnia magna Neonates Exposed to Single and Composite Mixtures of Four Emerging Contaminants

Pinos-Vélez, Verónica; Moulatlet, Gabriel M.; Pérez‐González, Andrés; Cipriani-Ávila, Isabel; Tripaldi, Piercósimo; Capparelli, Mariana V.

doi:10.1007/s00128-022-03663-8

Cited by 3 publications

(3 citation statements)

References 43 publications

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“…This helps in classifying substances based on their toxicities and in determining the doses appropriate for subsequent studies. Generally, substances with 48 h EC 50 values <1 mg L −1 are classified as very toxic to aquatic life 40 . According to the results of our acute toxicity test, TCS can be considered highly toxic to M. macrocopa as its reported 48 h EC 50 is 0.539 mg L −1 .…”

Section: Discussionmentioning

confidence: 85%

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Toxicity of triclosan, an antimicrobial agent, to a nontarget freshwater zooplankton species, Moina macrocopa

Samarakoon,

Fujino

2023

Environmental Toxicology

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The toxicity of triclosan (TCS) on the freshwater cladoceran Moina macrocopa was investigated by acute and chronic toxicity assessments followed by genotoxicity and oxidative stress response analyses. The 48‐h LC50 of TCS for ≤24‐h‐old M. macrocopa was determined as 539 μg L−1. Chronic exposure to TCS at concentrations ranging from 5 to 100 μg L−1 showed a stimulatory effect at low concentrations (≤10 μg L−1) and an inhibitory effect at high concentrations (≥50 μg L−1) on growth, reproduction, and population‐growth‐related parameters of M. macrocopa. The genotoxicity test results indicated that TCS concentrations ranging from 50 to 100 μg L−1 can alter individuals' DNA. Analysis of the antioxidant enzymes catalase (CAT) and glutathione s‐transferase (GST) demonstrated increased levels of these enzymes at high TCS concentrations. Our results indicated that TCS concentrations found in the natural environment have minimal acute toxicity to M. macrocopa. However, TCS at even low concentrations can significantly affect its growth, reproduction, and population‐growth‐related characteristics. The observed responses suggest a hormetic dose–response pattern and imply a potential endocrine‐disrupting effect of TCS. Our molecular and biochemical findings indicated that high concentrations of TCS have the potential to induce oxidative stress that may lead to DNA alterations in M. macrocopa.

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Section: Discussionmentioning

confidence: 85%

“…Generally, substances with 48 h EC 50 values <1 mg L À1 are classified as very toxic to aquatic life. 40 According to the results of our acute toxicity test, TCS can be considered highly toxic to M. macrocopa as its reported 48 h EC 50 is 0.539 mg L À1 . This value is comparable to that for other cladocerans (Table 4).…”

Section: Discussionmentioning

confidence: 91%

Toxicity of triclosan, an antimicrobial agent, to a nontarget freshwater zooplankton species, Moina macrocopa

Samarakoon,

Fujino

2023

Environmental Toxicology

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“…4 Traditional approaches to water toxicity assessment oen use lethality as an endpoint to evaluate the effects of a wide range of chemicals in the aquatic environment. [5][6][7][8][9][10][11] Other studies focus on physiological changes in response to sublethal concentrations of pollutants such as growth, reproduction, respiration, swimming activity, and ingestion of food, which are more sensitive readouts than survival in freshwater organisms. [12][13][14][15][16][17] Feeding activity, specically, is impaired by various environmental changes, such as the availability of resources and the presence of pollutants.…”

Section: Introductionmentioning

confidence: 99%

Development and application of a sensitive feeding assay for daphnids based on the ingestion of fluorescent microparticles

Giannouli,

Panagiotidis,

Rochfort

et al. 2023

Environ. Sci.: Adv.

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Solar photocatalysis application in UWWTP outlets - simulations based on predictive models in flat-plate reactors and pollutant degradation studies with in silico toxicity assessment

Grčić,

Radetić,

Miklec

et al. 2024

Journal of Hazardous Materials

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Acute Toxicity of Daphnia magna Neonates Exposed to Single and Composite Mixtures of Four Emerging Contaminants

Cited by 3 publications

References 43 publications

Toxicity of triclosan, an antimicrobial agent, to a nontarget freshwater zooplankton species, Moina macrocopa

Toxicity of triclosan, an antimicrobial agent, to a nontarget freshwater zooplankton species, Moina macrocopa

Development and application of a sensitive feeding assay for daphnids based on the ingestion of fluorescent microparticles

Solar photocatalysis application in UWWTP outlets - simulations based on predictive models in flat-plate reactors and pollutant degradation studies with in silico toxicity assessment

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