Editorial on the Research Topic Acute symptomatic seizures and epileptiform abnormalities: Management and outcomesEvery brain can produce an epileptic seizure. A key distinction is whether it is provoked or unprovoked. This dichotomy alludes to the identification of a temporally-associated etiology. When it is present at the time of, or immediately preceding, a seizure, they are called acute symptomatic seizures (ASyS). The insult-to-ASyS time window is etiologydependent, ranging from 24 h to 7 days and longer (1). Conceptually, the idea of seizure risk reduction after reversing underlying etiology is quite appealing. However, most ASyS are secondary to a non-reversible etiology, such as acute brain injuries (2), and exert a far more significant impact than traditionally appreciated. Assumptions and assertions about these "transitory" events have prevented systematic investigations into ASyS management, outcomes, and its natural history determination. The most glaring example underlies its fundamental defining feature-seizures within 7 days of acute brain injuries-proposed initially for "epidemiological studies" (1), which now pervades clinical practice. While seizures after the arbitrarily chosen 7 days have different outcomes than ASyS (3), emerging data suggest that ASyS after 3 days of injuries like stroke have similar implications (4). Needless to say, it is time to rethink ASySs and their standing in clinical epileptology.Convulsive ASyS are ubiquitous in clinical practice and, depending on geographical location, account for 40-50% of all afebrile seizures (5). Convulsive ASyS, including ones from metabolic insults, undoubtedly increases the risk of epilepsy development (epileptogenesis) (5,6). Prognostic models for symptomatic epilepsy development find ASyS contributing the highest risk among predictors of epileptogenesis (7,8). As a corollary to the classic dictum of seizure begets seizure (9), if a brain can generate a seizure (ASyS) once, it is easier for it to produce an unprovoked, remote symptomatic seizure as well, i.e.,