Acute Subjective Effects of Psychedelics within and Beyond WEIRD Contexts

Graziosi, Marianna; Singh, Manvir; Nayak, Sandeep M.; Yaden, David B.

doi:10.1080/02791072.2023.2255274

Cited by 1 publication

(1 citation statement)

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“…In modern-day research, extensive literature has documented alterations in consciousness during intense psychedelic treatment sessions 50 , 51 . Lacking sophisticated neurobiological research tools and methods, pre-prohibition researchers relied on patient reports and clinical observations to understand the medical psychedelic experience 21 .…”

Section: Clinician-reported Phenomenology In Psychedelic ‘Peak’ Therapymentioning

confidence: 99%

A rapid narrative review of the clinical evolution of psychedelic treatment in clinical trials

Kishon,

Modlin,

Cycowicz

et al. 2024

npj Mental Health Res

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Pre-prohibition psychedelic research with complex psychiatric patients generated a wealth of treatment methodologies and practices, providing invaluable clinical insights pertaining to the medical administration of psychedelics in various mental health diagnoses. Building upon these early studies, which lack the rigor and research tools available today, contemporary psychedelic research has focused on investigating the safety and efficacy of psychedelics in randomized controlled trials via psychometric measures and symptom assessments. Both then and now, the treatment context and the role of clinicians in psychedelic treatment has been recognized as an essential feature for positive patient outcomes. To broaden the knowledge base of modern psychedelic research and support the training of clinicians conducting medically supervised psychedelic research studies, this paper provides a review of pre-prohibition clinical research narratives pertaining to the phenomenology of psychedelic treatment and the role of the non-pharmacological treatment factors in the patient experience. Lastly, this paper explores a range of clinician perspectives and psychological interventions employed in pre-prohibition psychedelic research to inform future research directions and best practice guidelines.

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Section: Clinician-reported Phenomenology In Psychedelic ‘Peak’ Therapymentioning

confidence: 99%