Acute Stroke Assessment with CT: Do We Need Multimodal Evaluation?

Abstract

The presented multimodal CT evaluation improves detection rate and prediction of the final size of infarction in comparison with unenhanced CT, CT angiography, and perfusion CT alone.

Perfusion CT in Acute Ischemic Stroke: A Qualitative and Quantitative Comparison of Deconvolution and Maximum Slope Approach

“…The high quality of CBF and CBV maps found in our study has been reported in numerous publications; 2,3,28,30 our findings additionally show that CBF and CBV maps of DC and MS are very comparable in terms of quality and diagnostic value. In cases with poor source dataset quality, CBF DC and CBV DC maps were slightly superior to CBF MS and CBV MS maps.…”

Reperfusion by Combined Thrombolysis and Mechanical Thrombectomy in Acute Stroke: Effect of Collateralization, Mismatch, and Time to and Grade of Recanalization on Clinical and Tissue Outcome

“…Multimodal stroke CT, combining NECT, CTA, and PCT, demonstrated its feasibility to assess patients with acute stroke. 23 The next step toward a more individualized therapy of stroke was to use an intra-arterial application of rtPA, which was recommended as an alternative therapy beyond the 3-hour time window. 24 Most publications use the recanalization success and the clinical outcome as a treatment control and do not correlate their data to tissue outcome.…”

Multimodal Imaging Does Not Delay Intravenous Thrombolytic Therapy in Acute Stroke

“…2 Multimodal CT increases the sensitivity of stroke detection as well as the prediction of the final size of the infarct, compared with unenhanced CT, CTA, and PCT alone. 12 Moreover, these CT methods can be used immediately after unenhanced CT, they can be used to exclude hemorrhage, imaging time is fast (Ͻ 5 minutes), and no special hardware is required. 13 Second, fewer trips to the CT scanner during a patient's hospital stay reduce both transfer-related complications and clinicians' and CT technologists' workloads, increasing efficiency.…”