Acute Soft Head Syndrome in Children with Sickle Cell Anaemia in Lagos, Nigeria

Acute soft head syndrome and a mini review of bone and neurologic complications in patients with sickle cell disease

“…Acute soft head syndrome is characterized by progressive skull pain and swelling that occurs spontaneously without a recognized history of trauma. It is a rare complication in patients with SCD and few cases only have been reported in the literature (7,8,9).…”

Spontaneous subgaleal hematoma in a patient with sickle cell disease: A case report and literature review

“…Subgaleal hematomas can be classified into traumatic and non‐traumatic hematoma. In SCD, spontaneous subgaleal hematoma is a very rare complication of unclear pathophysiology, with few cases reported in the literature …”

Non-traumatic head swellings in a child with a sickle cell disease presented to a tertiary hospital North of Tanzania: A case report

“…Mainly this is secondary to thinning of the skull bone cortex due to chronic infarction occurring after repeated occlusion of its vessels. In addition, vessel wall necrosis along this area can cause non-traumatic bleeding to occur (Akodu et al, 2014). Another postulated mechanism is the extravasation of the overactive marrow of SCD patients through the weakened bone cortex to the outside (Hanafy et al, 2019).…”