Acute Sleep Deprivation is Associated with Increased QT Dispersion in Healthy Young Adults

Özer, Orhan; Ozbala, Burcu; Sarı, İbrahim; Davutoğlu, Vedat; Maden, Emin; Baltaci, Yasemin; Yavuz, Sema; Aksoy, Mehmet

doi:10.1111/j.1540-8159.2008.01125.x

Cited by 36 publications

(22 citation statements)

References 36 publications

(45 reference statements)

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“…Electrocardiographic abnormalities in cardiac conduction and repolarization resembling a proarrhythmogenic profile have also been detected after acute experimental sleep deprivation 64,65 .…”

Section: Epidemiologic Evidencementioning

confidence: 98%

Sleep Duration and Cardiovascular Disease Risk

Covassin

Singh

2016

Sleep Medicine Clinics

213

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Synopsis Inadequate sleep has become increasingly pervasive, and the impact on health and quality of life remains to be fully understood. The cardiovascular consequences alone appear to be substantial and significant. This brief review summarizes epidemiologic evidence regarding the association between extremes of sleep duration and the prevalence and incidence of cardiovascular diseases. The adverse effects of experimental sleep loss on physiological functions are discussed, along with those cardiovascular risk factors that may underlie the association with increased morbidity and mortality. Current data support the concept that inadequate sleep duration confers heightened cardiovascular risk. Thus implementation of preventative strategies may be needed to reduce the potential disease burden associated with this widespread high-risk behavior.

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Section: Epidemiologic Evidencementioning

confidence: 98%

Sleep Duration and Cardiovascular Disease Risk

Covassin

Singh

2016

Sleep Medicine Clinics

213

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“…Empirical studies have shown that short sleep time is the reason for possible unfavorable oncologic, endocrinologic, immunologic, and metabolic effects [21,22]. In addition, we have previously demonstrated that even one night of SD is associated with significant increase in electrocardiographic P and QT durations and dispersions [4,23]. However, exact physiopathological ways to elucidate this issue have not been described sufficiently.…”

Section: Discussionmentioning

confidence: 94%

Effect of acute sleep deprivation on heart rate recovery in healthy young adults

et al. 2014

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“…(4) Ozer O et al clearly demonstrated that even one night of sleep deprivation significantly increased QT max, QTd & cQTd in healthy young adults despite remaining within normal limits. (6) The present study examined the effects of sleep duration on QT and QTc intervals in normal weight and obese subjects. This present study also supports the hypothesis that sleep deprivation propentiates obesity and increases QTc intervals.…”

Section: Discussionmentioning

confidence: 99%

“…QT interval was measured by computerized measurements from limb lead II. (6) RR interval is the interval between an R wave and the next R wave. The RR interval from the preceding cardiac cycle is measured from the peaks of the R waves to correct the QT interval for heart rate (QTc).QT intervals were corrected with Bazett's formula.…”

Section: Objectivesmentioning

confidence: 99%